| Objective:To investigate the application of Wave Intensity (WI) technology incardiovascular function in the patients who have renal hypertensive.Materials and methods:There are30renal hypertension cases who lived in the department ofnephropathy in our hospital form February2013to August2012,16of the30cases with simple renal hypertension (age35.27±3.91),14renal hypertensioncases with renal dialysis (age38.02±4.28);32normal cases (age36.87±4.51) asthe control group. The ultrasonic diagnostic instrument Aloka Prosound a10was used before WI analysis, patients lie in left lateral position, start the AdultHeart, on the standard section of the left ventricular long axis, according to theM type to collect the parameters as below: left-ventricular end systolic diameter(LVEDs), left-ventricular end diastolic diameter (LVEDd), left-ventricularseptum end-diastolic thickness (IVST), left-ventricular posterior wall thickness(PWT), left-ventricular ejection fraction (EF), Left ventricular fractionalshortening rate (FS), stroke volume (SV), cardiac output (CO), and through theapex of the four-chamber view to obtain the corresponding value of leftventricular diastolic function (early and late diastolic peak velocity E peak, Apeak) and E/A. Start WI the difference of EF between kidney dialysis group,renal hypertensive group and normal control group, all have statisticallysignificant (p <0.05), the difference of FS between all groups, all have no statistical significance (p>0.05). The difference of E peak between kidneydialysis group and normal control group, it has statistically significant (p <0.05). The difference of E/A ratio, A peak between the three groups, all have nostatistical significance (p>0.05). The difference of W1, β between kidneydialysis group and simple renal hypertension, it has statistically significant (p <0.05). The difference of R-W1, W2, AC, AI W1, W2between the three groups,all have no statistically significant (p>0.05). The difference of NA betweenkidney dialysis group and normal control group, it has statistically significant(p <0.05), the difference of β、EP、PWVβ between kidney dialysis group andnormal control group, all have significant difference (p <0.01).Conclusion:In this study the difference of W1between kidney dialysis group an renalhypertensive group, it has significant difference (P <0.05), the former higherthan the latter, and the difference of EF was statistically significant, comparedto the EF and FS that Wl is to more sensitive, more obvious advantage onevaluate renal hypertensive cardiac systolic function in patients. Comparedwith normal control group, the Ep, β, PWVβ increased significantly (P <0.01)in kidney dialysis hypertension group, and the AC is lower than the normalcontrol group, so as to reflect that carotid arterial compliance and elasticitydecreases and the stiffness increased in the renal function: adjusting the BeamSteer (B) key, measuring each parameter of WI, the results are as follows: waveintensity of instantaneous acceleration(W1), negative wave area (NA), wave intensity of instantaneous deceleration (W2), Arterial elasticity parameters-carotid artery stiffness (β), vascular pressure-strain elastic modulus (Ep),,carotid artery compliance (AC), increase index (AI), pulse wave conductionvelocity (PWV β), and then analyze its relevance.Results:The age difference between simple renal hypertension group, renal dialysishypertension group and normal control group, there have no statisticalsignificance (p>0.05); the difference of systolic pressure, diastolic pressure,average pressure of three groups, all have significant difference (p <0.01).Height difference, it has no statistical significance (p>0.05). Comparisonbetween the three groups, age, height, body weight, heart rate body surface areaand body mass index (BMI), all have no statistical significance (p>0.05). Thedifference of LVEDS, LVEDd, IVST and PWT between renal dialysishypertension group and normal control group have statistically significant (p <0.05), the left ventricular wall thickness between simple renal hypertensiongroup, renal dialysis hypertension group and the control group,(p <0.01) allhave significant difference. The difference of SV and CI between simple renalhypertension group, kidney dialysis group, blood group and normal controlgroup, all have no statistical significance (p>0.05), the difference of CObetween renal hypertensive group and normal control group, it has statisticallysignificant (p <0.05), hypertensive patients. The index is a new way ofthinking on evaluation comprehensive function of the heart and blood vessels, the application of WI technology in the assessment of cardiac function in renalhypertensive patients, the evaluate cardiac function via peripheral vascular wasextended from now on. And the evaluation technology of left heart systolic anddiastolic function is more rapidly, early assessment can be made beforemorphological change on endothelial function in patients with renalhypertension. WI technologies provides a simple, noninvasive, rapid andreliable method for clinical course and outcome of renal hypertensive patients,it has a broad application prospect in clinical practice and play an importantrole in diagnosis. |
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