Effects Of Periodic Prophylaxis On The Periodontal Health Condition And The IL-17Level In GCF Of Patients With Fixed Orthodontic Appliances

Objective:Patients with fixed orthodontic appliances were gave prophylaxis in different period. The IL-17level in GCF and periodontal clinical index were observed before and during fixed orthodontic treatment to evaluate the effects of different periodic prophylaxis to the health of the periodontal tissues, and to discuss the best periodic prophylaxis of these patients.Methods:41patients wearing the straight wire appliance were divided into three groups. Group A accepted prophylaxis monthly, Group B accepted prophylaxis trimonthly, Group C accepted prophylaxis every six months(control group). we chosed The right maxillary first molar(16), the left maxillary central incisor (21), the left mandibular first premolar or the second (34/35) and the right mandibular central incisor (41) as index teeth. The GCF volume and plaque index, gingival index and probing depth were examined, and the IL-17level in GCF were detectde by ELISA.Results:1. Periodontal indexes:the plaque index and gingival index were significantly higher than the ones pretreatment in group A (P<0.05) at the1st month; In group B, the plaque index at the1st,3rd month were significant higher than the one at pretreatment (P<0.05), and the gingival index at the1st,3rd,6th months were significant higher than the one at pretreatment (P<0.05); while in group C, the plaque index and gingival index at the1st,3rd,6th months were significantly higher than the ones at pretreatment (P<0.05), the probing depth at6th month were significant higher compared with pretreatment (P<0.05). The plaque index and gingival index of group A were significant lower than group B and group C at3rd month (P<0.05), while there was no significant difference between the latter two groups (P>0.05); there were significant differences among the three groups at6th month (P<0.05). There were no significant differences of probing depth among the three groups during the6month treatment (P>0.05) 2. The GCF volume:the GCF volume of the three groups were significant higher at1st,3rd,6th months than pretreatment (P<0.05). At3rd month the GCF volume of group A were significant lower than group B and group C (P<0.05), while there was no significant difference between the latter two groups (P>0.05); there were significant differences among the three groups at6th month (P<0.05)3. The level of IL-17:In group A the level of IL-17was significantly higher than the ones pretreatment (P<0.05) at1st month; while in group B and group C, the level of IL-17were significant higher at1st,3rd,6th months than pretreatment (P<0.05). At3rd month the level of IL-17of group A were significant lower than group B and group C (P<0.05), While there was no significant difference between the latter two groups (P>0.05); there were significant differences among the three groups (P<0.05) at6th month.Conclusions:1.Prophylaxis can maintain the health of periodontal tissue of the fixed orthodontic patients, and the shorter of the cycle of prophylaxis, the better of the maintenance effect.2.Prophylaxis monthly can well maintain the health of periodontal tissue of the fixed orthodontic patients, but orthodontic doctor should choose the appropriate cycle of prophylaxis according to the different periodontal health condition.3.There were significant positive correlation among the GCF volume, the level of IL-17in GCF and the plaque index, gingival index, probing depth. The GCF volume and the level of IL-17in GCF can be effective index to evaluate the periodontal health condition of fixed orthodontic patients.