Endometriosis Patients Fundamental Temperature Curve Type And The Correlation Of Syndrome Types

ObjectiveThrough to the endometriosis patients the type of fundamental temperature analysis, this paper discusses endometriosis patients fundamental temperature type and the correlation of syndrome differentiation type points; Endometriosis patients and pelvic inflammatory disease patients, the differences of fundamental temperature; Endometriosis patients different card type of fundamental temperature curve types and related index (CA125and sex hormone level) correlation; According to the regulation of traditional Chinese medicine from the whole, through the syndrome differentiation and treatment to guide the uterus the clinical diagnosis and treatment, improve the clinical symptoms, improve pregnant rate of diagnosis and treatment to provide the basis.Methods1. Collect met inclusion criteria of endometriosis patients, according to the Chinese medicine diagnosis and classification, divided into kidney blood stasis, qi stagnancy and blood stasis, thermal YuXie stasis, haemorrheological nature and blood stasis four card type, each card type selection15patients, a total of60patients EM groups of patients, while the selection of30cases of patients with pelvic infection as control group.2. Enrolled to two menstrual cycles are the fundamental temperature measurement, including endometriosis patients BBT group (n=120), divided into kidney blood stasis syndrome (n=30), qi stagnancy and blood stasis syndrome (n=30), thermal YuXie stasis syndrome (n=30), haemorrheological nature and blood stasis syndrome (n=30), pelvic inflammatory disease patients (control group)(n=60). Parallel improved BBT three standards score, the SPSS17.0statistical software, a time series forecast method of smooth the moving method of mean and multivariate statistical processing variance analysis, comparison endometriosis patients the particularity of the fundamental temperature, and the foundation of patient pelvic inflammation temperature types and different card type between patients with fundamental temperature type of difference.Results1. This topic research object for endometriosis and pelvic inflammatory disease patients, EM group mean age,29.43±2.181years old, pelvic inflammatory disease patients (control group) mean age,28.37±5.216years, according to the frequency distribution, age are concentrated in27～32years old, the age for the women of reproductive age women, has the high fertility asked about.2. EM group of BBT and pelvic inflammatory disease patients (control group) comparison:(1) Collect EM group of120BBT groups, the control group of60group BBT according to frequency distribution, EM group of follicular period for17days25.8%, corpus luteum period for12days27.5%, visible EM group of patients with fewer slightly long period, and corpus luteum period (12.04±1.55days) a normal level (14±2days) should be short, both exist no differences (P>0.05); The control group of follicular period for15-16days33.4%, corpus luteum period for13days33.3%, visible pelvic inflammation of the patients of corpus luteum (13.03±1.22days) and normal level (14±2days) quite, there was no difference (P>0.05) adopt independent t test samples, vi sible EM with a control group of follicular period compared BBT there days (*P<0.01).(2) According to the data, using the time series forecast method of smooth the moving method of mean form the prediction model, low temperature control of EM visible than high temperature, low temperature of EM group is36.5℃above, and the control group is36.4℃lower, the temperature is36.736.8℃for a top. EM group high temperature period, low temperature phase is on the high side. EM group of high temperature is obviously the number of days than the control group to short.(3) The menstrual cycle in the first five days fundamental temperature obvious fell a delay of EM45%(54/120) a cycle, including minimum temperature is36.1℃, the highest temperature of36.8-37℃, with a median of36.5℃; And pelvic inflammatory disease patients (control group) no cycle5days before the BBT delay decline, including minimum temperature of36℃, the highest temperature is36.736.9℃, with a median of36.3-36.4℃. EM with a control group Dl-between D5, the multivariate analysis of variance, the comparison between the difference was statistically significant (P<0.01). In corpus luteum period before5days fundamental temperature rise by an average of<0.3℃, EM group is65%(78/120) a cycle, the control group was30%(18/60) of cycles, two groups*P<0.05, with a statistical significance.(4) EM group than the control group did score between the BBT improvement, and both are belong to corpus luteum poor or poor quality of its function. One group of corpus luteum function EM level is the worst, P<0.05, a statistically significant difference.Can deduce that endometriosis patients fundamental temperature types exist specific, concrete can be summarized as BBT low temperature phase arrhythmias (high temperature, low temperature period is on the high side, follicular period slightly long) corpus luteum function not health (corpus luteum period short delay in high temperature rise).3. EM group four different type certificate of the comparison:(1) EM group of four different card type. Each card type take30groups BBT, carries on the analysis of variance, different card type of follicular BBT between period and corpus luteum period days are difference (*P<0.01), further comparison between two of the variance analysis, blood stasis syndrome and the rest haemorrheological nature three card type BBT follicular period and the difference of corpus luteum days are statistically significant (▲P<0.01), the others each card type is no difference between both.(2) According to the data, using the time series forecast method of smooth the moving method of mean the forecast model of formation, visible four card type of low temperature is>36.5℃, the highest temperature of36.8℃to36.9℃, especially qi stagnancy and blood stasis syndrome and kidney blood stasis syndrome performance obviously. High temperature phase are performing for corpus luteum function not health, including kidney blood stasis syndrome, qi stagnancy and blood stasis syndrome, hot YuXie stasis syndrome of transitional period (by low temperature stage to the high temperature period) are>3d, high temperature end fundamental temperature drops slowly, blood stasis syndrome haemorrheological nature of high temperature fluctuations in big, more than0.2℃to0.3℃, and high temperature phase short days than11days.(3) Before the menstrual cycle four days of the BBT one-way anova, qi stagnancy and blood stasis syndrome and hot YuXie stasis syndrome haemorrheological nature and blood stasis syndrome differences (**P<0.05), including the menstrual cycle has significant difference D1(▲P<0.01). Comparison between two more than the variance of inspection were no statistical significance. EM patients in corpus luteum period before5days BBT rise by an average of<0.3℃, variance analysis, multiple line between different card type (*P<0.05), with a statistical significance. Haemorrheological nature of blood stasis syndrome and hot YuXie stasis syndrome, kidney blood stasis syndrome and qi stagnancy and blood stasis syndrome has significant difference (▲P<0.01).(4) Four syndrome types in patients with EM FSH and LH, E2level and CA125compares are difference in patients with level of EM low progesterone, four syndrome types are between statistical significance, other FSH on the high side, LH is low, accounting for55%.To the extent from specificity, qi stagnancy and blood stasis syndrome and kidney blood stasis syndrome patients than other card type more inclined to appear in low temperature BBT on the high side, and blood stasis syndrome haemorrheologiccal nature is in disorder tends to be high temperature. From improved BBT three standards score look, endometriosis patients than pelvic inflammatory disease patients tend to corpus luteum function not rehabilitation, and blood stasis syndrome haemorrheological nature than other card type of corpus luteum function level difference. In CA125and sex hormone levels of the more, four card type no significant differences.ConclusionThe curve of the BBT reflects the change of ovarian hormones, and TCM syndrome differentiation have identical place. According to the change of the traditional Chinese medicine can be as BBT symptoms of the basis of classification, for Chinese medicine diagnosis and provide objective basis and enrich the content of the TCM syndrome differentiation. On the basis of endometriosis patients temperature type, combining of the patient’s history and signs of clinical diagnosis of endometriosis have some help. In the diagnosis and treatment, the qi stagnancy and blood stasis syndrome and kidney blood stasis syndrome, take the traditional Chinese medicine for kidney and liver, can affect fundamental temperature, more help to adjust the endometriosis patients ovarian oviposit function. We put the BBT used in diagnosis and treatment, can be as a diagnosis, treatment and determine the curative effect of objective evidence.