Endoscopic Sclerosing Agent Injection For Treatment Of Mallory-Weiss Syndrome

Objective To investigate the effect of endoscopic sclerosing agent injection on treatment of Mallory-Weiss syndrome.Methods The58patients who diagnosed as Mallory-Weiss syndrome by immediate endoscopy and received endoscopic therapy were randomly divided into2groups: endoscopic aethoxysklerol injection(n=29) and endoscopic1:100000epinephrine injection(n=29). The hemostasis rate, re-bleeding rate and complication rate were compared.Result Initial hemostasis in therapy group was96.55%. Initial hemostasis in control group group was93.10%. There was no significant difference (P>0.05). The rate of early re-bleeding in therapy group was7.41%, which was significantly lower than that of29.63%in control group. The rate of re-bleeding in the near future and long-term in therapy group was both3.57%, while which in control group was both3.70%, and there was no significant differences between the2groups. There was no patient complicated of ectopic embolism, perforation and death in the two groups.Conclusion Endoscopic aethoxysklerol injection is better than endoscopic1:100000epinephrine injection in treating Mallory-Weiss syndrome.