The Cut Sinisan Square Clinical Study Of The Treatment Of Multiple Sclerosis

Objective:The observed use of the differences in efficacy of Sini San Decoction treatment of multiple sclerosis and Western glucocorticoid treatment of MS, as well as drugs associated with mining, and delve into the pathogenesis of MS, further summarize, sum up the rule of law and prescription of Chinese medicine treatment of MS,Methods:1.With reference to Western diagnostic criteria for multiple sclerosis (MS), combined with traditional Chinese medicine syndrome diagnostic criteria into patients, enrolled patients were divided into TCM syndrome treatment group (study group) and comparison group.2.Chinese medicine treatment group (study group) use of hormones or gamma globulin treatment for the acute phase of the observation period, the stable patients taking Chinese medicine; WM control group during the observation period is not used traditional Chinese medicine and the occasional use of traditional Chinese medicine patients, the application of Chinese medicine time for the patient's own average recurrence interval of1/4. The two groups observed a course of March2010and March2012, before and after treatment were neurological dysfunction score and check before and after treatment immunological examination TB lymphocyte subsets (CD3and CD4and CD8and CD25) and Th helper cells (Thl, Th2cells) changes.3.Data Processing:SPSS statistical software for statistical processing of the results obtained,setting P<0.05was considered statistically significant. The correlation analysis method using the correlation analysis program developed in cooperation of the Institute of Teaching and the Institute of Systems Science, Xiyuan Hospital clinical cases acquisition system. Count data with x2test; measurement data using the t test, paired t test. The correlation analysis is based on the Institute of Teaching and the Institute of Systems Science, Xiyuan Hospital of China Academy of Traditional Chinese Medicine to develop clinical cases acquisition system, the correlation analysis program.Results:l.An observation group of25patients taking traditional Chinese medicine treatment for more than the average recurrence interval in the past, including seven patients with relapse-free during treatment, three have relapsed during the treatment period, but the recurrence interval is greater han the previous average recurrence interval, the remaining15patients by continuous use of Chinese medicine, although so far no recurrence, but treatment is shorter than the previous average recurrence interval, recurrence interval prolongation after treatment of traditional Chinese medicine, there were significant differences (P<0.05) compared with the traditional Chinese medicine treatment before the recurrence interval. 2.observation group and25in the control group and20were annual relapse frequency of1-2times,3times,4-6times, more than seven times divided into four levels in the observation group were6,6,94, the control group were4people,5,8,3. The results show that the majority of patients in both groups, relapse are less than4-6times. The two groups of patients with relapse frequency difference (chi-square test, P<0.05) from relapses in the control group than the observation group.3.the observation group, the average recurrence interval of26.6months longer than the control group of18.2months, the average recurrence period of the Chinese medicine group and the average recurrence period of the control group were significantly different (P<0.05). The Atractylodes Professor Li Tao used a combination of drugs and licorice; Atractylodes, Aurantii; Bupleurum, Licorice; white peony root, Citrus aurantium; Atractylodes, Bupleurum;Bupleuri, Aurantii; licorice, soil Fuling.The use of Chinese medicine used in the treatment of multiple sclerosis Professor Li Tao from highest to lowest for a licorice, Atractylodes, white peony root, Bupleurum, Citrus aurantium.Discussion:Multiple sclerosis is a common participation from both humoral and cellular immune utoimmune diseases; Hase and other reports suggest that multiple sclerosis increased Thl-type cells to secrete cytokines in peripheral blood of patients in the acute phase, while Th2cells secrete cytokines to reduce remission on the contrary, the Th1/Th2balance changes for the aggravation of multiple sclerosis and outcome is essential to prove, we have that Qi stagnation Decoction treatment can reduce the Th1level, a lower level of Th1T cell immunity tends to be a normalsign.The study builds on the Qi stagnation and Treatment of multiple sclerosis on the basis of Qistagnation side Yupingfengsan and Sini San Fang, studies have shown that Sini DecoctionDecoction treatment of multiple sclerosis patients can effectively reduce recurrence, delaying disease progression in patients with the control group can also be reduced in patients with recurrence, delaying disease progression in patients, but the effect is better observed therapeutic effects. Mining by the old Chinese medicine Chinese medicine dosage higher frequency of the system analysis, licorice, Atractylodes, white peony root, Bupleurum, Citrus aurantium, composed of Sini Decoction Decoction, clinical studies have shown that these drugs have to modulate the immune and anti-inflammatory role; Atractylodes, Licorice; Atractylodes, Citrus aurantium; Bupleurum, Licorice; white peony root, Citrus aurantium; Atractylodes, Bupleurum;Bupleurum,Citrus aurantium these drugs to the spleen and in the high frequency, its compatibility tips, sparse The mechanism of liver qi stagnation, liver and Liver, liver and gas main, visible Sini Decoction Decoction treatment of multiple sclerosis may be associated with this group of prescription drugsmodulate the immune and anti-inflammatory effects, liver and gas law treatment of multiplesclerosis.