The Application Value Of 24 Hours Ambulatory Electroencephalography Monitoring In Children With Cerebral Palsy

ObjectiveTo explore the application value of 24 hours ambulatory Electroencephalography (AEEG) monitoring in children with cerebral palsy. To explore the relations between the AEEG and the type,the class, epilepsy or other complications of children with cerebral palsy.MethodsWe conducted a clinical study based on 165 children with cerebral palsy referred to the Rehabilitation Center of Qilu Children s Hospital of Shandong University from October 2008 to October 2009.A11 the 165children with cerebral palsy were examined by the monitoring of 24 hours AEEG. The AEEG was recorded on a 8-channel AEEG system, Electrodes were attached to the scalp with collodion according to the 10-20 system, and the child's head was wrapped to decrease the likelihood of electrode displacement. A diary was completed by the parent to register the specific time, duration, and clinical description of any event.76 cases were undergoing both AEEG and EEG inspection,and their manifestation were read by one and the same Electroencephalographic Technologists.Results1. AEEG abnormalities were seen in 52.12% of 165 children with cerebral palsy. Of the 76 cases which undergoing both AEEG and EEG inspection,the positive finding of abnormality rate and epileptiform discharge by AEEG was obviously higher than routine EEG(x2=9.70,P<0.01; x2=13.40, P<0.01).2. The time of epileptiform discharges were mainly during sleeping (97.29%).3. Significant difference of AEEG abnormal rate was found in various clinical types of cerebral palsy (x2=34.20,P<0.01).The highest AEEG abnormality rate was spastic hemiplegia (76.00%),followed by spastic quadriplegia (66.67%), dyskinetic was the lowest (11.11%).4. Generalized seizures were the most common (55.56%) clinical type of seizures in children with cerebral palsy.5. There was a significant difference in the abnormality rate and epileptiform discharge of AEEG between children with Seizures group and Seizure-free group (X2=28.86, P<0.01; x2=58.52, P<0.01).6. AEEG abnormalities were seen higher in children with mental retardation group than children without mental retardation group(x2=55.12, P<0.01).Conclusions1.24 hours ambulatory Electroencephalography has very important application value in children with cerebral palsy.2.24 hours ambulatory Electroencephalography can increase the detection rate of epileptiform discharges.3. Children with cerebral palsy epileptiform discharges happened mainly during NREMⅠ-Ⅱ.4. The positive finding of abnormality rate in children with cerebral palsy by AEEG is related with the location of cerebral injury.5. The most of the clinical attack and AEEG characters of CP children with EP are Generalized seizures. 6. The abnormal AEEG rate of the children with cerebral palsy which complicated with epilepsy or mental retardation was higher.