The Clinical Research On Lacunar Infarction With The Treatment Of Tonifying Qi And Blood And Resolving Stasis

Objective:To explore mechanism of action on treatment of Lacunar Infarction with tonifying Qi and blood and resolving stasis, verified the curative effect and security of Kangshuan capsule, and the evidence for clinical popularization of the medicine can be provided.Methods:According to inclusion criteria,60 patients were randomly classified into two groups:the therapy group with 30 cases were given Kangshuan capsule besides basic therapy, the comparison group with 30 cases were given Weinaolutong tablets besides basic therapy. There were two courses of treatment,14 days for one, and two days discontinuation between two periods. Observe patients diversity and security before and after treatment on neurologic deficits evaluation, TCM syndrome integral, indices, blood lipid, hemorheology and TCD. Statistical analysis from SPSS17.0 software processing, the measurement data using t-test, counting material using X2 test and the Wilcoxon were using on clinical curative effectResults:①n the clinical effect, the total effective rate of the treatment group was better than control(90%,76.67%), with statistically significant difference(P<0.05).②The neural function defect scale:score of treatment group below the control group, with highly statistically significant differences(P<0.01).③TCM syndrome:various syndromes in treatment group improved significant than in control group, with highly statistically significant differences(P<0.01).④lood lipid:TC,TG and LDL-C in treatment group were obviously lower than controls, with highly statistically significant differences(P<0.01).⑤emorheology:treatment group indexes compared with the control were significantly lower, with highly statistically significant differences(P<0.01).⑥CD:the speed of average blood flow in the brain artery in treatment group significantly better,with highly statistically significant differences (P<0.01).Conclusion:The remove blood stasis and double replenishing method is an effective TCM treatment,and the kangshuan capsule is curative effect precisely and safety, deserve application in clinical.