Investigation And Analysis Of Dyslipidemia Among Kazakh And Hans Population In Northern Xinjiang

Objective:To investigate and analyze the distribution of dyslipidemia and the influencing factors between Kazakh and Han nationalities aged 18 and above in northern Xinjiang area.Methods:11,A Questionnaire-based survey was carried on physical examination and blood testing were conducted according to cluster random samplings in Kazakh and Hans residents, aged 18 and above in northern Xinjiang.2,Using the way of home visit to collect information related to the questionnaire, physical examination and blood specimen collection.3,Serum total cholesterol (TC), triglyceride (TG), low density lipoprotein cholesterol (LDL-C), high density lipoprotein cholesterol (HDL-C), fasting plasma glucose (FPG) were measured by OLYMPUS 2007 automatic biochemical analyzer.4,All statistical analyses were performed using the SPSS 17.0 statistical software. Normal distribution data was descriped as (x±s), the measurement data between the two groups were compared with t test number, the number of multiple groups were compared using single factor analysis of variance; non-normal data using the median and P2s～P75 description, the comparison between the two groups using non-parametric test; count data was used to compare the rate of trend Pearsonχ2 test andχ2 test; Multivariate non-conditional Logistic regression analysis of the factors of dyslipidemia.Results:Total investigate population was 7341, including 3935 people of Kazakh nationality (1567 males and 2368 females), average age is (44.23±13.21) years old; 3406 people of Hans (1434 males and 1972 females), the average age is(49.94±12.34) years old.1. Prevalence of dyslipidemia:Kazakh and Hans crude prevalence rates were 40.9% and 41.0%, after age-standardized, the Kazak and Han prevalence rates were 40.8% and 36.2%(P <0.05), the Kazakh hypertriglyceridemia, high TC hyperlipidemia and high LDL-C hyperlipidemia and low HDL-C hyperlipidemia detection rates were 18.1%,12.6%,6.3% and 18.5%; Hans high TG hyperlipidemia, high TC hyperlipidemia, high LDL-C hyperlipidemia and low HDL-C hyper- lipidemia detection rates were 30.6%,11.4%,4.3% and 4.2%. Kazakh people with high LDL-C hyperlipidemia and low HDL-C hyperlipidemia detection rate is higher than Hans the Hans, the Hans population is higher than Hans the detection of high TG hyperlipidemia Kazakh people.2. Lipid levels:TG, TC, LDL-C and HDL-C average level:Kazakh were 1.00 (0.69～1.49) mmol/L, (4.58±1.32) mmol/L, (2.42±0.87) mmol/L and (1.31±0.61) mmol/L; Hans were 1.32 (0.92～2.00) mmol/L, (4.62±1.08) mmol/L, (2.22±0.94) mmol/L and (1.63±0.70) mmol/L. The average level of Kazakh serum TG was significantly lower than Hans(P<0.05), TC average Kazakh and Hans was no significant difference, the Kazakh LDL-C average is significantly higher than Hans (P<0.05), the HDL-C average is significantly lower than Hans (P <0.05). TG, TC, LDL-C and HDL-C levels were an average of the trend increases with age. Multivariate Logistic Regression Analysis.3. Kazakh population:Multivariate Logistic regression analysis showed that male, overweight and obesity, central obesity, diabetes, smoking are risk factors for dyslipidemia; the amount of drinking tea, vegetables and fruits are protective factors of dyslipidemia. Risk factors of high TG:agriculture and livestock, abdominal obesity, overweight and obesity, smoking, and bean products; protective factor is drinking tea. High-TC risk factors are age, hyperlipidemia, abdominal obesity, high blood pressure, and the amount of drinking tea, vegetables and fruits were protective factors; High LDL-C risk factors are age, hyperlipidemia, abdominal obesity, diabetes, aquatic products; Low HDL-C risk factors are male, smoking, aquatic products and ages, the amount of drinking tea, drinking, milk, vegetables and fruits are protective factors.Hans multivariate analysis showed that the dyslipidemia risk factors are hypertension, overweight and obesity, diabetes; High-TG risk factors are hyperlipidemia abdominal obesity, overweight, obesity and diabetes; High-TC risk factors for hyperlipidemia are abdominal obesity, diabetes, and ages; High LDL-C risk factors are hypertension hyperlipidemia and fried foods; Low HDL-C hyperlipidemia protective factors are abdominal obesity and smoking.4. Kazakh and Hans dyslipidemia constituent ratio of different types of aggregation:Kazakh highest detection rate of dyslipidemia is hypertriglyceridemia with high TG and low HDL-C hyperlipidemia and Hans highest detection rate of dyslipidemia is hypertriglyceridemia, and high TC hyperlipidemia.Results:1. Kazakh and Hans groups prevalence of dyslipidemia was higher than the national average level. Kazakh is higher than Hans, males is higher than females.2. Kazakh hyperlipidemia prevalence of high TG is lower than Hans, Kazakh people with high LDL-C hyperlipidemia and low HDL-C hyperlipidemia prevalence rates are higher than Hans, the two national high prevalence of hyperlipidemia TC have no differences.3. Kazakh and Hans prevalence of lipid abnormalities were detected:Hans have a high prevalence of high TG dyslipidemia, Kazakh have a high prevalence of low HDL-C dyslipidemia.4. Kazakh population LDL-C level was significantly higher than Hans population, and TG, HDL-C was significantly lower than the Hans people. Kazakh and Hans male TQ LDL-C levels were higher than females, male's HDL-C lever lower than females.5. Kazakh dyslipidemia risk factors are male, overweight and obesity, Central obesity, Diabetes, smoking are risk factors for dyslipidemia; Hans dyslipidemia and risk factors are hypertension, overweight and obesity, diabetes.