Clinical Study Of E₂, P,β-HCG On Bu Shen An Tai Prescription For Kidney Deficiency Incipient Abortion

Purpose:Observation on the clinical efficiency of using the Bu Shen An Tai prescription on kidney deficiency incipient abortion patients, as well as the function mechanism.Method:Separate forty five patients of clinic and ward into either treatment or control group according to their function of treatment. Fifteen cases among the control group are given twenty milligram progesterone intramuscular injection per day. It can be given addition amount according to individual cases. The patients of treatment group are also given the same amount of progesterone, but using the Bu Shen An Tai prescriptions in addition for treatments. The course of each treatment is four weeks. We observe both groups for one course of treatment. The observation is based on the improvement of main symptoms, levels of E2,P,β-HCG of both groups patients before and after medications. This bring the analysis and determination of curative effect and safety issues of the medicine.Consequence:Determine the treatment efficiency according to symptoms accumulate points: Treatment group:Recovery rate 46.67 percent, markedly improvement rate 36.67 percent, valid rate 13.33 percent, invalid rate 3.33 percent, overall valid rate 96.67 percent. Control group: Recovery rate 33.33 percent, markedly improvement rate 13.33 percent, valid rate 40 percent, invalid rate 13.33 percent, total valid rate 86.67 percent. Through the rank-sum test (P<0.05), it is found that the treatment efficiency of treatment group is better. The symptoms accumulate points for both groups are decreased remarkably after treatments. The difference has made statistical significant through T test. The difference of symptoms accumulate points for both groups from before and after treatment have made statistical significant through T test (P<0.05) as well. The difference of treatment group is larger than control. This shows that the treatment efficiency is better on treatment group. The levels of sex hormone E2,P,β-HCG for both groups are higher from before to after treatment. It has statistical significant through T test (P<0.05). This illustrates that the treatment bring escalating trends on sex hormone for both groups. The differences between sex hormone from before to after treatment have statistical significant through T test (P<0.05). The difference of treatment group is larger than control group shows that it has advantage on improvement of sex hormone. In addition, the variations of E2 from before to after treatment have obvious reference significant to treatment efficiency through T test (P<0.01). There is no adverse reaction for both groups of patients during treatment period.Conclusion:It is more efficient on using Bu Shen An Tai treatment to kidney deficiency incipient abortion patients. It is clearly improve the symptoms of vaginal bleeding, abdominal pain and soreness of waist etc. This treatment also improves the levels of E2, P andβ-HCG. The variations of E2 in the period of treatment have obvious reference significant to the treatment efficiency. Therefore, Bu Shen An Tai treatment is an valid method on ameliorate the symptoms of incipient abortion patients and regulation of endocrine function. The values of E2 have more obvious conference significant to P andβ-HCG during the observation of treatment effect.