The Mechanism Study Of Dahuangzhechong Bolus On Liver Cancer

Objective: To observe the Etiology and Pathogenesis and treatment of liver cancer and the mechanism of Dahuangzhechong Bolus on liver tumor through theory and experimental study.Methods: In the respect of theory:Elaborate Blood stasis and Cancer toxic is the main factors of Liver cancer Etiology and Pathogenesis with Ancient literature and Modern research. So Treatment should based on the idea Quxie not make improper righting. In the respect of experimental study:To Observed the effect of Dahuangzhechong Bolus about tumor growth of H22 tumor-bearing mice and the angiogenesis on chick embryo chorioallantoic membrane in the role of Dahuangzhechong Bolus Serum. Result: Dahuangzhechong Bolus can improve the quality of life, stabilize or enhance body weight , the big dosage group and the little dosage compare with the control group have distinct difference on the carcinoma weight (P<0.01), Dahuangzhechong Bolus Serum can inhibited the number of blood vessels of 5-7d Chorioallantoic membrane. Conclusion: Dahuangzhechong Bolus can inhibit the growth of liver tumor and Improve quality of life; Dahuangzhechong Bolus Serum can inhibited the number of blood vessels of Chorioallantoic membrane clearly. Prompt that Dahuangzhechong Bolus may inhibit angiogenesis and thus play the role of hepatic tumors.