| According to particle diameter in the atmosphere,the particle which Dp≤10μm called inhalable particle(PM10). It can enter human respiratory apparatus. The particle which Dp<5μm called respirable particle(PM2.5). It can enter human lung alveolus. The powder particles can be inhaled can not only to air to polluting damage, but also bring influence on the human body of the upper respiratory system.Because the upper respiratory system connects the human body with the natural environment.After understanding pathogenesis mechanism on the respiratory system diseaseat.At the same time,it is used to correct the way of inhaled preparation of strength and spray device which sprays particle size. Under the premise of designing and studying the structure of the device to medicine,this paper is is to make numerical simulation of the oral-upper respiratory system.In order to deeply understand powder particles about the deposition in the upper respiratory system, eatablish a perfect three-dimensional geometry model including oral cavity,pharynx,larynx,trachea and bronchi of the upper respiratory tract.in this paper.At the same time,this research will provide theoretical references for inhale in the flow field. In this article, the Euler-Lagrange coordinate system of gas-solid two-phase flow of discrete model (discrete phase model, DPM) is used, through the solution Navier-Stokes equations to simulate the flow of the calculation area,then to solve the primary flow and particle deposition in three breathing intensity such as 15L/min,30L/min,60L/min. Eighteen kinds of the particles arc selected. They are different in diameter as follows:0.5μm,1.0μm,1.5μm,2.0μm,2.5μm,3.0μm,3.5μm,4.0μm,4.5μm,5.0μm,5.5μm,6.0μm,6.5μm,70.μm,7.5μm,8.0μm,9.0μm,10.0μm. With respiratory intensity and particle size changing, the inhalable particles deposition rate in the different position of upper respiratory tract is summarized. |
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