| Purpose: Observation of rabbits Lithospermum typeâ…¢hypersensitivity, Treatment of allergic purpura Zicao mechanism of action.Material and method:By egg albumin-Freund 's complete adjuvant, emulsifier type hypersensitivity causedâ…¢rabbits were randomly assigned into normal group, model group and the Radix decoction group, to observe the skin reaction time the degree of application of PEG precipitation measuring levels of serum CIC , ELISA determination of serum levels of IL-2,from skin tissue morphology by light microscopy pathology.Results:1. Lithospermum Tangâ…¢type hypersensitivity model in rabbits at different time points after the formation of typeâ…¢can inhibit hypersensitivity in rabbits.2. Lithospermum Tang rabbit serumâ…¢type hypersensitivity circulating immune complexes are decreasing.3. Lithospermum Tangâ…¢type hypersensitivity rabbit serum IL-2 levels decreasing.4. Lithospermum inhibitory effect on rabbitâ…¢type hypersensitivity skin under the light microscope the number of neutrophils.Conclusion:1. Lithospermum Tang inhibitoryâ…¢type hypersensitivity reaction to the role of skin irritation.2. Lithospermum Tang inhibitâ…¢type hypersensitivity in rabbits Decoction on circulating immune complexes (CIC) levels, IL-2 levels inhibit trend.3. Lithospermum Tang inhibitâ…¢type hypersensitivity, may be its role in the treatment of allergic purpura one of the mechanisms. |
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