From The Literature Review And Experimental Study Of Wind On The Treatment Of Allergic Asthma

Allergic asthma are clinical common and frequently-occurring I-allergic disease, which is the body created by the antigen-specific immune response after stimulation caused by tissue damage and/or physiological dysfunction of a disease. The disease is scattered among a number of diseases in traditional medicine, can also be expressed as an independent disease, which is mainly caused by exogenous allergen-induced tissue damage and physiological dysfunction. Our incidence of allergic asthma on the rise, seriously affecting people's physical and mental health. Therefore, treatment and prevention of the occurrence of allergic asthma is of great significance. This study not only for clinical prevention and treatment of allergic asthma to provide some ideas, but also for Chinese and Western medicine with prevention and treatment of allergic asthma to provide experimental evidence and a new way.lObjectiveThrough Theoretical studies have confirmed pathogenic wind and allergic asthma etiology and pathogenesis and the incidence of illness, treatment-related; Obtained by experimental study with Supplemented Guo Min Jian prevention and treatment of allergic asthma fried experimental data to explain its anti-allergic mechanisms, from the pathogenic wind treating Allergic Asthma provide theoretical and experimental basis for the guidance.2 Methods2.1 Theoretical methodsIn this study, literature and data, logic analysis and statistical methods, pathogenic wind pathogenicity as well as the ancient literature on the pathogenesis of allergic asthma in the literature should be straightened out to explore the ancient physicians of pathogenic wind and allergic asthma machine and the incidence of illness, treatment understanding of the relevance.(1) Analysis of ancient literature, the classification of asthma, allergic asthma screening that belongs to the documentary record.(2) Research Etiology and Pathogenesis of Allergic Asthma(3) studies of allergic asthma symptoms (4) Analysis of various types of asthma the frequency of drug use, focusing on part of the treatment of allergic asthma probability of drug use.2.2 Experimental methods2.2.1 Experimental animalsThirty-six Sprague Dawley male rats, weighted 180-260g, brought from Beijing Weitong Lihua animal study center, Were randomly divided into normal control group, asthma model group, fried treatment group with Supplemented Guo Min Jian,12 rats in each group. Apart from the normal control group, rats in each group every two days after intraperitoneal injection of lml antigen solution (containing egg protein100mg, aluminum hydroxide 100mg, Bordetella pertussis vaccine 5×109piece) allergen. The normal control group, intraperitoneal injection of equivalent normal saline.14d sensitization after drug treatment with Supplemented Guo Min Jian, The normal control group and the asthma model group were given equivalent normal saline, 1h after the neb nebulised medication in order to stimulate ovalbumin inhalation asthma, drug delivery and stimulate continuous 14d. lhour after the last excitation started experimenting with drawn. All rats received natural light, ate and drank freely, and were controlled under certain room temperature was 17℃±2℃in winter and spring, and it was 25℃±2℃in summer and autumn.2.2.2 Test methodTo assay the contents of IgE, ELISA was engaged.2.2.3 Analysis methodThe differences of groups were tested by SPSS 13.0. All the data were showed by mean±standard error. P<0.05 meant obvious difference. P<0.01 meant very obvious difference.3Results3.1 Results of theoretical studypathogenic wind and allergic asthma mechanism and the incidence of illness treatment with closely related.3.2 Results of experimentsSerum IgE levels of asthma model group was significantly higher compared to normal control group(P<0.01). Treatment group with Supplemented Guo Min Jian can significantly reduce the IgE levels (P<0.05), compared with the asthma model group with significant difference. This study showed that asthma model group animals's serum IgE level was significantly increased with I-type allergic reaction characteristics. 4 Conclusions4.1 The occurrence of allergic asthma is closely related to the invasion of pathogenic wind. In this study, literature and data, logic analysis and statistical methods, pathogenic wind pathogenicity as well as the ancient literature on the pathogenesis of allergic asthma combing literature research, recognizing pathogenic wind and allergic asthma machine and the incidence of illness treatment with close relationship.4.2Supplemented Guo Min Jian could therapy allergic asthma. Experimental observation that Supplemented Guo Min Jian can reduce the levels of IgE, inhibit allergic inflammation in asthma, indicating that Supplemented Guo Min Jian could treate the allergic asthma, and its mechanism of action may be related to anti-inflammatory exudation, anti-allergy and its further-depth study of the mechanism remains to be femtocell.