Shu Lee, Triple Burner, Thanh Hoa Hot And Humid Particles Of The Women's Shower The Perimenopausal Of Urinary Tract Infection Intervention Experimental Studies

1 BackgroundPerimenopausal is a period from the reproductive age of women to the disabled age. Because of the particular physiological changes, Perimenopausal women have high incidence rate of urinary tract infection, which is easy to recurrent and hard to be cured. To the great suffering of patients, clinical treatment in the use of antibiotics combined estrogen obtains a certain effect, but did not reduce the incidence of the disease and the recurrence rate, and long-term use of antibiotics leads to resistance problems and increases the difficulty of clinical cure of the disease. Traditional Chinese medicine believes that the disease is " Lin syndrome " category. There are a lot of treatments on disease experience and discourse, which are limited to clinical cases of lessons learned, but less Experimental disease-specific research and proprietary Chinese medicines.2 Theoretical basisAccording to Professor Jiang Liangduo instructor of "the external diseases based on internal injuries ", internal injuries often leads to the atypical and complexity of the presence of external disease, external diseases also affect the internals. Perimenopausal women are in a special period of physiological changes, with Chong and Ren Mai asthenia, Tian Gui drying up, liver deficiency of essence and blood, liver dystrophy, so that the normal liver catharsis can not affect the accessibility of the triple burner.Triple burner is the place of human gasification, but also for the body of water fluid metabolism in the road, poor triple burner is easy to lose bladder gasification Division.Therefore,Qin Ying in the group of instruction considered that the key to the pathogenesis of this disease is Liver Qi stagnation, triple burner poor, hot and humidity gathering in the bladder,and invented Fu Lin Granule on the basis of clinical experience.The subject was designed to study the infection of Fu Lin Granule to the perimenopause urinary tract on animal study.3 Experimental MethodsExperimental part of this issue is divided into three parts:1 animal model:With the two basic points "perimenopause" and "urinary tract infection", the mice were and infected in urinary tract, with vaginal smear method for the ovariectomied results and the bladder bacterial infection of the urinary tract and bladder pathological grade to evaluate the results;2 drug intervention:Fu Lin Granule (classified into large, medium and small three doses), San Jin Table and levofloxacin (combined with conjugated estrogen tablets) were used on the animal model intervention, and with the establishment of model group, sham infection group and sham ovariectomy group, a total of eight treatment level results were evaluated just like in the animal model part.Besides, there was a self-designed independent activity experiment, groups were compared by observing mice differences in the number of specific actions at the same time, in order to reflect the different treatments on neuropsychological status in perimenopausal Intervention;3 in vitro inhibition experiment:With San Jin Table as control sample,we used the method tube dilution to evaluate the inhibition bacteria effect of Fu Lin Granule.4 Conclusion1 animal model experiment:the vaginal smear results, bacterial infection results in the bladder and bladder pathological grade results are in line with expectations.2 drug intervention results showed that:There were no significant differences among Fu Lin Granule group, western medicine and Chinese medicine control sample groups,but the contrast among model group, sham ovariectomied group and sham infected group indicated that ovariectomy factor has increased the extent of urinary tract infection, which might be the evidence from experimental for the point of view of the teacher "external diseases based on internal injuries theory"; For spontaneous activity in the intervention, the role of Fu Lin Granule group was significantly higher than the control group, indicating their state of mind in adjusting the neural advantages, reflecting the method "dredging triple burner, clearing heat and removing dampness"has good effects on the organism's overall adjustment.3vitro inhibition experiments show that Fu Lin Granule has good antibacterial or bactericidal effect, reflecting Fu Lin Granule in the "dispelling evil" role.In conclusion, these three experiments showed that both internal injuries and external diseases based on it were dramatically effected by the method "dredging triple burner, clearing heat and removing dampness",which adjusted the overall state of the body significantly and made organism safety.