Early Pregnancy Of Women's Reproductive Tract Chlamydia Trachomatis Infection Of Il-2, Il-6, Il-8 Detection And Significance,

Objective To explore effects of Chlamydia trachomatis on local and systemic immune status Of infected in early pregnant women by detecting the experimental group and control group levels of IL-2,IL-6,IL-8 in cervical secretions and serum.Methods Women in early pregnancy who were for treatment in the out-patient of Obstetrics and Gynecology in the First Hospital of Shanxi Medical University from July 2008 to December 2008 were enrooled.Early pregnancy of CT infection in high-risk groups were carried out conventional polymerase chain reaction of Chlamydia trachomatis(CT-PCR) detection. Twenty early pregnant women with Chlamydia trachomatis-infected reproductive tract(experimental group)and 20 early pregnant women without infection of reproductive tract (control group) were enrolled.The cervical secretion and serum were collected.The levels of IL-2,IL-6 and IL-8 were detected by radioimmunoassay.Using SPSS 11.5 statistical software to analysis the datas.Mean±standard to deviate the results.Using t-tests to compare the mean between the two groups,P＜0.05 means there were statistically significant difference.Results Compared with control group,the levels of IL-2 and IL-8 in cervical secretion increased in experimental group(P＜0.05),but the level of IL-6 showed no significant difference between 2 groups(P＞0.05).There was no statistical significance in the levels of IL-2,IL-6 and IL-8 in serum(P＞0.05).Conclusion Chlamydia trachomatis-infected in patients with early pregnancy can affect the local immune of reproductive tract,IL-2 or IL-8 may be involved in the process of the local immune in early pregnant women with Chlamydia trachomatis-infected reproductive tract.Its impact on the state of the body is not significant.