| Objective:To observe clinical effect of Gongmi powder on the treatment of chronic cervicitis cervical erosion.Method:1.Subjects : 110 cases of chronic cervicitis and cervical erosion (damp invasion of lower energizer) were chosen. The methods used were randomly divided into two groups, one group falling three cases, the control group shedding two cases, it is divided into: Observer Group (Gongmi powder treatment group) of 65 cases, the control group (Aibaoliao treatment group) of 40 cases . The two groups were no significant difference (P > 0.05) in age, course of disease, illness grade, the average Chinese medicine treatment Syndrome points, Chinese individual symptoms (the minor), the sub and type of cervical erosion, colp-clearing grade, were comparable.2. Treatments : Observer Group, on the medicine by physicians: dry cotton ball lightly with disinfection James stem the cervical and vaginal secretions , And gynaecological equipment will be dedicated cervical powder into the mouth, so that the spray evenly covered in the Department of cervical erosion , ask patient to hospital the next day on the drug once, eight times for one treatment. The control group, on the medicine by physicians the first in the hospital, with dry cotton ball to disinfect the surface of cervical and vaginal secretion Of wipe clean, there will be love-treatment Baptist concentrated liquid into the Cotton cervical, turning several times removed, and then re-use, such as large or slightly larger than the erosion of gauze to block the Baptist-treatment and enrichment of love, oppression lightly Application In the lesions, for five minutes, so that lesions to become white, on the 2nd at night before going to sleep at home to the vagina near the deep love of cervical-treatment and disposal of the bolt-1; later on the 3rd to repeat the hospital for treatment of a A course of treatment.Two ways administ in 3-7 days after menstruation clean, the next menstrual clean after three days of review, to the second course of treatment if no cure, during treatment ban bath and Sex life, drugs will be disabled during menstruation . Observation of two courses.3. observatian indexesPrincipal indexes: the size of cervical erosion surface, the degree of inflammation; secondary indexes: the integral of traditional Chinese medicine syndrome penthemeron, colp-clearing grade.Security indexes: general physical examination, blood routine, urinary routine, stool routine, electrocardiogram, ALT, BUN, Cr.4.Curative effect assessment:Principal curative effect assessment: the size of cervical erosion surface, the degree of inflammation; secondary curative effect assessment: the integral of traditional Chinese medicine syndrome penthemeron, colp-clearing grade.5. Statistical treatment:The measuement data had been analysed by t test, and the enumeration data been analysed by chi-square test(including one based on the likelihood ratio chi-square test). While the ranked data had been tested by Ridit analysis. P > 0.05 demonstrate no significant difference , P < 0.05 demonstrate has significant difference, P < 0.01 demonstrate has highly significant difference.Results:1. In the size of cervical erosion surface and the degree of inflammation, the total efficiency of the observer group was 95.38%, While the total effective of the control group was 87.50%,;in the integral of traditional Chinese medicine syndrome penthemeron, the total efficiency of the observer group was 87.69%, the total efficiency of the control group was 67.50%; in the improvement of colp-clearing grade, the Observer Group has 69.23% after treatment with vaginal secretion cleanliness into I°, The control group was 47.50%, the two groups were all significantly different (P <0.05). It stateed that the therapetic efficiency of gongmi powder was better than Aibaoliao.2.In the more casual of leucorrhea, unusual colors of leucorrhea, lumbar falling flu and abdominal distention, Genital itching, the clinical symptoms have improved significantly, the effect was better than aibaoliao, there were significant differences (P <0.05); The urine Lin Li Shibuya pain, bleeding and other symptoms of contact with aibaoliao, no significant difference (P> 0.05).3. Gongmi powder treatment group as correlation analysis results showed that the effect of age and no correlation, and the course of disease, illness and the effect of a significant correlation, the shorter the duration or more light condition, the more obvious effects.4. The erosive effects of Gongmi powder was associated with the area, the smaller the area, the effect of the better. Type of erosion and the effects are also relevant, simple effect of the best.5. Follow-up conditions, all cured patients review after six months , the relapse rate was 5.88% (Gongmi powder group), 26.67% (Aibaoliao group), the difference was significant (P <0.05). It indicated that the recent recurrence rate of Gongmi powder was lower than Aibaoliao.6. There was no abnormal changes for the treatment group in blood routine, urinary routine, stool routine, hepatic function, renal function and electrocardiogram after the treatment. Gongmi powder had no harmful reaction, and it was safe in the course of clinical application.Conclusion:Gongmi powder can eliminate fever and deprive the evil wetness, discard septic and promote tissue regeneration. It can treat chronic cervicitis and cervical erosion (damp invasion of lower energizer) ,the therapetic efficiency is better than Aibaoliao ,can significantly improve clinical symptoms, especially for the treatment of mild to moderate, simple cervical erosion, the recent low rate of recurrence .Clinical application of safe and reliable no significant side effects. |
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