Hypertension Tcm Syndromes And Prescription Study

Hypertension is the most common seen cardiovascular disease, it has become a threat to human health and one of the main reason of death. People from all over the world had invest a tremendous amount of manpower and resources to make researches on hypertension. Western medicine had a quick effect in treatment of hypertension, but unresolved headache, dizziness, palpitation, tinnitus, insomnia and other symptoms. Moreover long-term medication will cause side effects on liver and kidney function. Combining Western Medicine and Traditional Chinese Medicine(TCM) is the best treatment for Hypertension. The most significant advantage of TCM treatment for hypertension is by combining the differentiation of symptoms and diseases in order to determine the right course of treatment. In TCM, kidney deficiency is the fundamental cause of Hypertension disease. Extensive research on Kidney deficiency Hypertension will improve TCM effect results on Hypertension treatment and improve the life quality of patient with hypertension.1. Literature and theory researchBy summarizing progress of modern medical hypertension treatment,the etiology of hypertension is related with both genetic and environment factors. To which genetic hypertension accounted for 30-50%. Environmental factor includes diet smoking alcohol obesity climate and stress; all could increased blood pressure. The major line of Hypertension pathogenesis is changes of hemodynamics renin-angiotensin-aldosterone system, insulin resistance, vasoactive substances. Western treatment of hypertension continue to develop a different treatment guidelines, updating categories and type of hypertension drugs ,through different antihypertensive mechanism trying to achieve more stable blood pressure and prevent complications. Western hypertension drugs is divided into seven main categories : diuretics calcium channel blocker, beta-blockers,α₁ receptor blockers, Angiotensin converting enzyme inhibitor (ACEI), angiotensin II receptor antagonist (ARB) and aldosterone antagonist. Recently There is a new categories of hypertension drugs : vascular endopeptidase inhibitors, renin inhibitors.In TCM there is no hypertension name, but In TCM classics《Neijing》already had a record about "headache" and "vertigo". Subsequently many doctors such as : Zhang Zhongjing, Zhu Danxi, Zhang Jingyue provide more theoretical foundation for "headache" and"vertigo". Pathogenesis of hypertension related with abnormal physical talent, emotional disorders, eating predilection, overstrain and overleisure. This disease is related with the liver, heart, brain, kidney, but mainly is closely connected with the liver and kidney. In TCM hypertension is divided to many kinds of syndrome: Liver yang hyperactivity syndrome Yin deficiency yang hyperactivity syndrome. Liver-kidney yin deficiency syndrome Liver essence deficiency syndrome,Phlegmatic syndrome,Blood stasis syndrome. The Treatment is using Tianma Gouteng Decoction,Qiju Dihuang Pills,Zhengan Xifeng Decoction,Banxia Baizhu Tianma Decoction, Xuefu Zhuyu Decoction, etc. Modern pharmacology has confirmed Chinese herb has antihypertensive mechanism such as : Liuwei Dihuang Pills had peripheral expansion,therefore lower peripheral resistance; Radix Stephaniae Tetrandrae had diuretic mechanism;Radix Puerariae had beta-blocker mechanism ; Radix Polygalae and Semen Ziziphi Spinosae had central antihypertensive mechanism.Many doctors agree with kidney deficiency hypertension views .Therapeutic principle using nourish kidney-liver yin,warm kidney yang, tonify kidney active blood, and get treatment efficacy by that. Modern Medical Lab result also show that throught tonify kidney therapeutic principle can improve test indicators.2. Ancient literature theory related to kidney deficiencyBy Summarizing Ancient literature records including etiology, pathogenesis, syndrome, and treatment prescription, They Provide us a clear evidence of theoretical basis for kidney deficiency hypertension.In Chinese TCM classics《Neijing》there already had records about "headache" and"vertigo" symptoms that related with kidney deficiency. Zhang Jingyue provide a clear basic treatment principle for "headache" and"vertigo"related with kidney deficiency. Kidney deficiency hypertension divided into 5 types: 1.Kidney essence deficiency that lead to the loss of brain essence,treatment principle is tonify kidney essence with Dabuyuanjian,Shouwu Yanshou Dan,etc; 2.Kidney Yin deficiency that lead to Liver Yang hyperactivity, treatment principle is nourish yin and suppress yang with Liuwei Dihuang Pills, Qiju Dihuang Pills,Dabuyin Pills,Ziyin Baweijian,etc; 3. Kidney Qi deficiency that lead to Phlegmatic-damp, treatment principle is tonify kidney, resolve phlegm and drain damp with Shenqi Pills; 4.Kidney Yang deficiency that lead to water invasion of the upper body,treatment principle is warm Yang and to drain fluids with Zhenwu Decoction; 5.Kidney deficiency that lead to blood stasis, treatment principle is tonify kidney and to move the blood Jingui Shenqi Pills.3. Summarizing Professor Wang Jie's clinical experience in treating hypertension.Professor Wang Jie thinks that combining Western Medicine and Traditional Chinese Medicine (TCM) is the best way for Hypertension's treatment. Based on TCM syndrome differentiation and Overall Analysis of the human body principal, to adjust the balance between yin and yang is the basic fundamental treatment for hypertension. Professor Wang Jie's thought on hypertension treatment is: 1.Disease integrating with syndrome. Professor Wang advocates that it is important not to just recognize the disease but also the symptoms, pathology, the characteristic of the disease etc (syndrome) .First recognize the disease then what kind of syndrome that it represents and then thoroughly differentiate all the information to determine a better treatment for the patient; 2.Content of diagnosis syndrome. It's important to differentiate the symptoms, the related organs and the patients physical condition, to determine the main symptom and not to be distracted by other unsignificant symptoms, correctly determine the related organ can help doctors to choose the right kind of treatment and also to understand clearly about the patient's physical condition will provide a clear treatment basis to begin with; 3.Prescription must corresponding with the syndrome. Treatment method depend on syndrome diagnosis,Prescription based on treatment method; 4.Using Effective drug. Using drug which has antihypertensive mechanism will improve TCM effect results on Hypertension treatment.4. Using Statistics looking for syndrome and prescription features on 50 cases of Hypertension disease.Using Access and Prescription Intelligent Software to make statistic on 50 cases of Hypertension disease.50 cases divided into 5 category:Kidney deficiency syndrome,Liver Yang hyperactivity syndrome,Transformation of lifer Yang into wind,Phlegmatic-damp syndrome and blood statis syndrome. Results: 1.Kidney deficiency syndrome. Most common symptoms is vertigo,deep thin pulse,lack of strength in the lower back and the knees, also had dry stool,yellow coating which mean that kidney deficiency syndrome easy transforms into heat,so in treatment method beside tonify kidney,also using clear heat method with Liuwei dihuang Pills. 2.Liver Yang hyperactivity syndrome. Common symptoms is:headache,vertigo,Petulance irritability, treatment method is to pacify liver and to clear the heat with Tianma Gouteng Decoction. 3.Transformation of lifer Yang into wind. Specific symptoms is vertigo,headache,numbness and dizzy vision, treatment method is calm liver and extinguish wind:Zhengan Xifeng Decoction. 4.Phlegmatic-damp syndrome. Common symptoms is vertigo,greasy coating,wiry slippery pulse, treatment method is dispelling the damp and to resolve Phlegm with Banxia Baizhu Tianma Decoction. 5. Blood statis syndrome. Common symptoms is purple tongue,choppy pulse,headache, treatment method is to move the blood and dissipate stasis with Xuefu Zhuyu Decoction.