Studies On Chemical Constituents Of The Sea Of ​​red Beans And Bitter Rope

Adenanthera pavonina Linn., the entire plant of Adenanthera pavonina Linn, in Leguminosae, had an effect on alleviating fever and disintoxication.The acetic ether portion of EtOH extract of this plant showed anti-inflammatory activities in vitro. Few reports about chemical and active constituents of this plant can be found in literatures. In order to understand its chemical constituents and find out anti-inflammatory compounds, the chemical constituents of the 95% ethanol extract of Adenanthera pavonina Linn, were studied. Thirteen compounds were isolated by column chromatographic methods such as silica gel, polyamide, Diaion D₁₀₁, ODS and Sephadex LH-20. On the basis of chemical evidence and spectral analysis, the structures of ten compounds were elucidated as aridanin (1), 3-[(2-acetamido-2-deoxy-β-Z)-glucopyranosyl)oxy]-16α-hydroxyolean-12-en-28-oic acid (2), (+)-pinitol (3), sucrose (4), butin (5), apigenin (6), isoliquiritigenin 4-methyl ether (7), oleanolic acid (8), daucosterol (9),β-sitosterol (10). Among them, compound 1, 2, 3, 4, 5, 6 and 7 were isolated from this plant for the first time.