T Peak - At The End Between Brugada Syndrome Risk Stratification Study

[Objective] To evaluate Tpeak-Tend (Tp-e) interval in surface standardECG as a new risk factor in patient with Brugada syndrome.[Methods] There were 23 patients (all male) with Brugada syndromeand 20 patients(all male) with paroxysmal supraventriculartachycardia(PSVT) in our study. Tp-e interval in surface standard ECGwas compared between BrS patients and PSVT patients.[Results] There was significant difference in Tp-e interval between BrSpatients and PSVT patients [(109.57±22.86)ms vs (88.50±13.08)ms,P＜0.05]. Tp-e interval in 16 BrS patients with arrhythmic events(such assyncope, clinical ventricular fibrillation[VF] and electrophysiologicalstudy[EPS] induced VF) was significant longer than 7 BrS patientswithout arrhythmic events and PSVT patients[(118.12±20.40)ms vs(90.00±15.27)ms, P＜0.05; (118.12±20.40)ms vs (88.50±13.08)ms,P＜0.05], but it was similar in BrS patients without arrhythmic events andPSVT patients [(90.00±15.27)ms vs (88.50±13.08)ms, P＞0.05].[Conclusion] The prolongation of Tpeak-Tend interval (Tp-e≥120ms)could serve as a new noninvasive risk factor for arrhythmic event inpatient with Brugada syndrome.