The Repolarization Reserve Function 0f Patients With Ventricular Premature Beat

Purpose: To investigate the value of corrected QT interval、QTd、Tp-ec interval、Tp-ed、Tp-e/QT ratio for The repolarization reserve founction in patients with ventricular premature beat.Methods:229 cases of sinus rhythm with ventricular premature beat were included,according to the recovery of QT interval in sinus cycle length behind ventricular premature beat,whose QT interval recovery was abnormal would be brought into the observation group, and the normal brought into the control group,To compare the differences of corrected QT interval、QTd、Tp-ec interval、Tp-ed、and incidence of ventricular tachycardia between two groups.Evaluating the diagnosis value of corrected QT interval、QTd、Tp-ec interval、Tp-ed、Tp-e/QTratio in patients with ventricular premature beat.Results:1.Between observation group and control group, gender, age, QTd had no statistical differences,corrected QT interval,Tp-ec interval,Tp-ed,and incidence of ventricular tachycardia had statistical differences.2.Under different heart rate,the change of corrected QT interval had statistical differences.3.Corrected QT interval,Tp-ec interval, Tp-e/QT ratio has diagnostic value to the repolarization reserve dysfunction, QTd has no diagnostic value.The best diagnosis boundary value of each index to repolarization reserve dysfunction is: male QTc ≥458 ms(sensitivity 52%,specificity 52%) and female QTc ≥ 469 ms(sensitivity 76%, specificity 58%), Tp-ec ≥ 95 ms(sensitivity 54%, specificity 86%), TPe/QT ratio ≥ 0.22(sensitivity 39%, specificity 91%).Conclusions: QTc, QTd, Tp-ec, Tp-ed, Tp-e/QT ratio as noninvasive indexes is applicable to evaluate the repolarization reserve function 0f patients with ventricular premature beat.And they can improve the accuracy of diagnosis if combined with the dynamic changing of QT interval after with ventricular premature beat.it has diagnosis value and guiding effect for SCD.