| With the rapid development of medicine science, more and more clinical medicine workers pay attention to evidence-based medicine, including Chinese medicine workers. This study provided a new thought for Chinese medicine to treat drug dependent. And this study received the help of Professor Lifeng, and the guidance of Cochrane Collaboration. The systematic review in this paper is one part of the title "Traditional Chinese Medicine for Opioid Withdrawal Syndrome" in Drugs and Alcohol group of Cochrane Collaboration. Its protocol has been published in Cochrane library in the issue 2, 2006, and the full text will be published in the next year.This study has two parts, systematic review and clinical investigation.Part 1 Systematic ReviewObjective To assess the effectiveness and safety of Chinese medicine in the treatment of opioid withdrawal syndrome.Methods We searched MEDLINE ( 1966-2005) , EMBASE (1974-2005) , The Cochrane Library ( Issue 1, 2005 ) , and some Chinese databases for additional articles ( CBMdisc, CMCC, VIP, CNKI ) (1980-2005) . The quality of included randomized controlled trials was evaluated and meta-analysis was performed with RevMan 4.2.Results We collected 138 titles in Chinese on Chinese medicine for opiod withdrawal syndrome, 18 in English, and 0 in Japanese. And we put the same together. At last, there were 24 titles internalized, including 6 titles of class A, 3 titles of class B, and 15 titles of class C. They were all in Chinese. We used meta-analysis to analyze 5 titles, including 3 titles about Shenfutuodu capsule and 2 titles about Lingyi capsule. They all aimed directly at acute withdrawal syndrome. |
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