Qi Stagnation, Blood Rheology Xiangdan Injection Treatment Of Angina Pectoris And Clinical Changes In Aptt

The coronary heart disease (CHD) is the main disease harming the mankind healthiness. Though the incidence rate of CHD in our country is lower than the west developed countries, in most part of our country, particularly the north or relatively developed area, this illness tends to be more and more and is becoming the main cause of death. Therefore, how to prevent and cure of CHD is also the focus of the medical research. Since the 10 years, with the development of percutaneous coronary intervention and reconstructive vascular operation, the medical level has been increased and the mortality decreased. In the same time, the medical cost has been raised greatly. Traditional Chinese Medicine (TCM) has many advantages in treatment of CHD. Many patients are treated by it or combination of TCM and western medicine and get benefit from them..Angina pectoris belongs to"Chest Bi"in the TCM. Its Pathogenesis is deficiency in the root and excess in the branch. The cause of deciency in the root is old age,feeble bold , excessive tiredness, poor appetite after long sick and so on. The Qi stagnant and Yang deficiency are common. The reason of excessive appearance is that pathogenic cold invading heart, excessive sentiment, too heavy food and so on. The well condition of chest is disturbed and the vessel of heart is blocked up, and resulting in stagnation of Qi and blood, phlegm-obstruction and cold coagulating. Due to appearance and substanse all being in disorder, deficiency mingling with excess,they shoud be given consideration to both two of them when being treated. The basic pathogenesis is Qi-stagnant and stagnation of blood. Qi- stagnant leads to stagnant blood and phlegm-muddiness that hindering in the vessel. The latter can also aggravate the Qi- stagnant and the vicious cycle occurs. Therefore, reinforcement and dredging therapies can benefit from each other. Manage Qi and activating blood are the basic methods to treat CHD.Xiangdan Glucose Injection is made up of Radix Salviae Mitiorrhizae and Lignum Dalbergiae Odoriferae.Radix Astragali, According to the Guidelines for Treatment of angina pectoris with Chinese Materia Medica, GUIDELINES FOR NEW DRUG CLINICAL TRIALS (1997 Edition3). we designed the clinical trials. We undertook this study to evaluate the effects and side effects of the treatment and APTT with Xiangdan Glucose Injection in angina pectoris patients.A total of 30 out-patients in cardiovascular internal madicine Dept of DongZhiMen hospital aged 40-70 years was studied. After 2 weeks of treatment, test drug...