Clinical Observation Of Xiangdan Tongluo Zhitong Decoction In The Treatment Of Unstable Angina Pectoris(Qi Stagnation And Blood Stasis Syndrome)

Purpose: Guided by the theory of internal carbuncle caused by heat poison,the patients with unstable angina pectoris treated with Xiangdan Tongluo Zhitong prescription and syndrome differentiation as qi stagnation and blood stasis were observed,and the clinical efficacy and safety of the patients were confirmed through the observation of the changes of symptoms of angina pectoris and the changes of TCM syndromes and other related indexes.Methods: The patients who met the long-term follow-up were selected from January2019 to February 2020 in the affiliated hospital of Changchun University of traditional Chinese Medicine.Seventy-two patients who met the inclusion criteria were randomly divided into 36 cases in the trial group,and the western medicine was given routine treatment plus Xiangdan Tongluo Zhitong prescription.Control group 36 cases,given western medicine routine treatment.The course of treatment was 4 weeks.After the treatment,the patients were observed in angina symptoms,TCM syndrome changes,ECG changes,cardiovascular events incidence,nitroglycerin withdrawal rate,Seattle score changes and other efficacy indicators,as well as the safety of the whole treatment process.Data entry S PSS.20.0 software for statistical analysis.Result:1.Effect of angina symptoms: after treatment,the total effective rate of the experimental group was 88.24%,compared with the control group 58.82%,Compared with the control group,the risk stratification of angina pectoris and the effect of symptoms grading of angina pectoris were statistically significant.2.TCM curative effect aspect: the total effective rate of the test group after TCM syndrome treatment was 91.18%,compared with the control group 55.88%,after examination,it was statistically significant.TCM symptom group comparison: in the chest tightness,chest and flank distention main symptom has the significant statistical significance.was statistically significant in chest pain,palpitations,and hypophthalmia.Group comparison: the primary and secondary symptoms before and after treatment in the experimental group were statistically significant,the control group before and after treatment in chest pain,good too rest,chest and hypochondriasis stuffy,in chest tightness,palpitations statistically significant;3.ECG changes: after 4 weeks of treatment,the total effective rate of electrocardiogram in the experimental group was 55.88%,and that in the control group was 52.94%.4.Comparison of malignant cardiovascular events :4 weeks after treatment,the two groups were statistically significant in the need for revascularization rate of myocardial infarction.There was no significant difference in the rate of new myocardial infarction.5.Reduction rate of nitroglycerin: after treatment,the reduction rate was 79.17% in the test group and 58.33% in the control group.6.Seattle score changes: the two groups compared after treatment,in PL、AF,there is statistical significance;in AS、TS、DP,there is significant statistical significance.Conclusion: On the basis of the routine treatment of western medicine,the application of Xiangdan Tongluo Zhitong prescription can effectively improve the symptoms of patients with Qi stagnation and blood stasis,and the clinical effect is remarkable.in the observation of the seattle scale,it can be seen that the drug has obvious advantages,improving the four major symptoms of angina pectoris and reducing the attack of angina pectoris;in traditional chinese medicine,both the curative effect of syndrome and the curative effect of symptoms are remarkable,which improves the quality of life of patients.