Advances In The Treatment Of Osteoarthritis Of The Knee

Osteoarthritis of the knee(OAK) is a common and frequently-occuring diseases in the middle and older, but it' Pathogen and pathology are not clear. The therapy of OAK could be divided into three parts: rehabilitation, medicine and surgery. The major medical therapies are the uses of the non-steriodal and- inflammatory drugs, the protection of articular and Chinese drugs. Intra-articular injection, arthro-washout, arthro-debridement, drilling are fit for the early stage. High tibial osteotomy and osteochondral or chondrocyte transplantation can be used in middle stage. And the arthrodesis and arthroplasty are fit for the last stage, but the arthrodesis has been used less than before. Additionally, genotherapy is going on the course of probing and research, which might bring the revolutionary influnce to the therapy of OAK. The rehabilitation is the foundation of above, which should be used in all stages.In the clinic trial hyaluronic-acid intro-articular injection (HA-IAI) added Traditional Chinese Medicine is superior to the pure HA-IAI. Chinese drugs of tonifying the liver and kidney are the best on the long-term effect, but affect slowly. And Chinese drugs of promoting blood circulation or dispelling cold, reducing phelm appear their effects quickly, but the effects don' t last long. Chinese drugs added HA-IAI is desirable to research. Prevention should be advocated by the treatment of tonifying the liver and kidney.