Experimental Study Of The True Wu Tang Co-su Ting Pill Treatment Of Pulmonary Heart Disease Complicated By Heart Failure

Chronic pulmonary heart disease combining cardiac insufficiency, is mainly manifested as cough,pant ing, expectoration,palpitation,short breath,edemac1inica1ly .that belongs to Pyndrome characterized by "dyspnea'' "Edema" "Palpitation" and "Lung-distention" of traditional chineses medical science. Traditional Chinese medicine think that the pathological changes location of this disease start from the lung.If the disease is not treated timely, pathologica 1 conditions aggravate gradually,and lead to that lung , spleen,heart and kidney are all deficiency and retention of phlegm and fluid and blood stasis block in the interior. It is a case with the syndrome of deficiency in origin and excess in superficia1ity.So we should carry out treatment based on syndrome differentiation according to different course of the disease. Clinica11y, when chronic pulmonary heart disease combines cardiac insufficiency, traditiona1 Chinese medicine think that syndrome type is often deficiency of heart and kidney yang, failure of lung to disperse and descend, f1uid retention and blood stasis blocking,and fluid retention invading heart and lung. So that therapeutic principles are mainly warming yang to promote micturition, checking upward adverse flow of qi,expelling phlegm and eliminating yin.Diuretic pecoction by strengthening yang of spleen and kidney derives from <> , it is a celebrated prescription of warming yang to promote micturition, timely is adequate for the pathogenesis of chronic pulmonary heart disease and cardiac insufficiency .Clinica1ly,a lot of doctors often use diuretic pecoction by strengthening yang of spleen and kidney to treat the chronic pulmonary heart disease and cardiac insufficiency. Curative effect is very good, secondly,we find that some doctors use Sutingwan or pepperweed seed singly to treat this disease,fault is also very good. Thus we investigated the combined prescription to know about wheath this combined prescription is better than respective singular prescription on the four aspects of expelling phlegm, re 1ieving asthma strengthening heart and diuresis.The result is that the combined prescription is better than respective singular prescription on the aspects of expelling phlegm ,relieving asthma , strengthening heart and diuresis,the statistical results of experiment data are all different obvLOUSly,P<0. 01 or P<0. 05; that the efficience of relieving asthma of combined prescription is higher than the respective prescription evidently.The experiment offers determinate foundation of pharmacology for treating Chronic pulmonary heart disease combining cardiac insufficiency clinically in future.