The Compound Hypoglycemic Mechanism - On Glucose And Lipid Metabolism

Objective: To investigate the action and mechanism of Shenqi Polypharmaceutical on how to influence diabetic rat's blood glucose regulating hormones and improve its supersession disorder state. Methods:Established DM rats by intraperitoneal injection of Alloxan are to be diveid randomly in five groups:model control,DM model treated with low dowsage middle dowsage and high dosage of SQ and BS group respectively.Normal control group is also set.After three week's treatment, detecting rat's following materials including BG, INS TC TG HDL C-P LDL both in am empty stomach state and postprandial state with the use of radioimmuno assay,meanwhile rat's pancreatic tissues are also made into pathological section for analysis.ResultDM rats do exist abnormality of the above mentioned materials,whose rising blood lipid level is one of important lipid metabolism disorder.SQ can improve the DM rat's high blood glucose metabolism disorder ,raising INS HDL content in serum whereas descending TCU TG LDL;accelerating the renovation and proliferation of the pancreatic B cells.The general curative effect of SQ is better than the west medicine corss-refer group. Conclusion:SQ can act in multiple ways and levels to degrade blood glucoe.