| Menopausal syndrome is the common disease and affects the life of the women.With the method of case-contrast in clinical , observing the symptom of body and psychology and life events is to analyze the character of the pattern in menopausal syndrome . By the correlated analysis among the semiology,symptom-sign ,measuring scale and detection index , it is to get the dangerous factor and the laws of TCM pattern identification in order to find the effective method for treating Menopausal syndrome.The thesis includes two part:Part one:Theoretical studyIn this part, the medicine in treating menopausal syndrome is discussed and the hypothesis of maladjustment is supposed.To carry out the statistic analysis of the medical herbs on curing menopausal syndrome, we find that the tallest medicine in frequency of occurrence and the dose is Chinese angelica, next is rehmannia dride rhizome , the medicine to benefit weak is the most , it occur 401 times and weight 4832g.By the means of the medicine,we know that the vacuity of kidney is the basic pathogenesis, the fuctional disorder of liver,spleen and heart is very important too.On the basic of the theory of TCM and the stress ,we raise the hypothesis of maladjustment: as the stressor ,the depression of kidney qi stimulate the body,which is not able to adjust this ,menopausal syndrome occurs.Part two:Clinical studyThe most common symptoms of menopausal women is hot flushes and sweat, the incidence is 63.2%. Other symptoms such as depression , anxiety, insomnia,impatience and irritability,headache,abnormity of the sense ,formication of the skin,are familiar too.There are more than forty kinds of patterns , the pattern of binding depression of liver qi is the most common one ,the incidence of which is 91.57%. Liver vacuity , kidney vacuity,middle burner dampness-turbidity stagnation ,heart vacuity ,blood stasis ,qi vacuity ,stomach vacuity ,gallbladder stagnation and phlegm stir and dryness invading lung are the main patterns,the incidence of which is above 50%. The incidence of yin vacuity is more than yang vacuity,but the patterns of yin vacuity and yang vacuity often come with each other. The pattern of qi vacuity is positively correlated with menopausal syndrome. FSH,LH and FSH/LH in the patient are more than the common women in menopause, E2 is less than the common one, but there is not obviously difference. The negative emotion is negatively correlated and the score of stress is positively correlatewith menopausal syndrome. The patients' score of anxiety and depression is obviously more than the common menopausal women, they are easy to be anxious and depressed.It is positively correlated between age with menopause and the score of the symptoms,the change of menstruation with the symptoms' score .Menopause is positively correlated with FSH,LH,FSH/LH, the score of Kupperman and symptom of stretch-shorten in blood vessel.It is negatively correlated with E2. There is negatively correlated between E2 and FSH,LH,FSH/LH,the score of stretch-shorten symptom in blood vessel. There is positively correlated between the score of symptoms and the score of anxiety and depression. From that ,we know that the occurrence of menopausal syndrome is not only the change of the body but also the mind.That the change in mood and the maladjustment in the decline of tiangui are important to the occurrence of menopausal syndrome. To adjust the mood is the main part to treat the menopausal syndrome. In this way, the body is to get the balance in the new internal environment, to regain health. |
