Undifferentiated Spondyloarthropathy Chinese Medicine Clinical Research

This study based on the theory of T.C.M and integrated Traditional chinese and western medicine, systematically explored the cause, patbogenesis am1 therapeutic method of undifferentiated spondyloaithropathy from theoretical and clinical aspects. re- seareh suggested that hiden pathogenic factor was the internal factor exsitimg during the whole course of the disease. Heat and dampness hiding in body is the key factor of pathogenesis progress. Accordingly, Bi Xiao Mug decoction was given based on the therapeutic method of clearing away heat and toxic materias, eliminating dampness iUid removing the obstruction in meridians. Clinical data of 42 uspA were analyzed, To e- validate their onset, clinical features, response to therapy, these cases were divided in- to two groups. The JuSpA group had acute onset, prominent manifestations of ex- traspinal, mild sacioiliitis (may be relevant to their growth characters), high hip joint involment compared with those of AuSpA(P<0.05),whileAuSpA group with axial in- flammatoiy back pain or hip pain as initial manifestations, having chronic onset are pre- dominent( P <0.05) . There was no significant difference in response to treatment (P> 0.05) Clinical and laboratory manifestations were improved significantly after therapy. Combined with the results of clinical and relative literature, the operating mechanisms of this method was investigated. All of these indicated that this method had the pro- nounced effect for the therapy of uSpA.