| Purpose:This topic through the application Chinese to qi treatmentresult (strong heart tonga origin, the dwarf lilyturf) treatment of qi and Yin and chronic heart failure patients with two empty type, watching the party of qi and Yin and chronic heart failure patients with two empty the therapeutic effect of type, and the treatment of chronic heart failure qi method for standard clinical research, intends to provide a practical for clinical and valuable way. Also with statistical methods of traditional Chinese medicine treatment of chronic heart failure detection treatmentresult time of traditional Chinese medicine, and the node curative effect in improving the treatmentresult advantages of TCM symptoms, and to evaluate curative effect strong heart tonga origin, the dwarf lilyturf clinical efficacy and safety, discussed the mechanism for future drug development to lay the foundation.Material and method:This clinical study of all patients were from liaoning university of traditional Chinese medicine hospital heart medicine July 2009 to 2010 July clinic patients, and conform to the diagnostic criteria and the inclusion criteria, total 60 cases. According to random number table by the random number according to 1:1 divided into the treatment group, the control group, 30 cases per groups. Using randomized method for the qualified subjects prospective randomized clinical research. The control group give western medicine standardized treatment, the treatment group in the western standard treatment on the basis of traditional Chinese medicine combined with qi treatmentresult (strong heart tonga origin, the dwarf lilyturf), drug composition 40g, ginseng 15g, astragalus 15g, danshen 30g red and raw land 20g, radix ophiopogonis 20g 20 g, notoginseng, motherwort 5 g, etc. Daily a agent, points three times oral. Observation time for 3 months, observe two groups before and after the treatment effect hf patients grading, cardiac function, integral, TCM symptoms, syndromes integral, the quality of life, integral change, and regular monitoring adverse reaction index. Results1.two groups of cases of the general conditions before treatment, cardiac grading, heart failure integral, syndromes total score, TCM syndrome grading and quality of life score by statistical methods, inspection, no significant difference (P > 0.05), explain two groups of comparable;2.Two cases of grading, cardiac function of the total effective rate (hf integral show + efficient), no efficiency, increase rate, there were no significant difference of statistics (P > 0.05), two groups of significant efficiency and efficient contrast significant difference (P < 0.05).3.two groups of patients total score syndromes in the treatment of January, February, march before treatment with itself controlled visible: treatment group total score and healing TCM symptoms are compared, differences before statistical significance, (P < 0.05) or P are all < 0.01); The control group total score and healing TCM symptoms are compared, differences before statistical significance, (P < 0.05) or both (P < 0.01); both Two groups of patients total score syndromes by statistical comparison between groups, the difference, t-test, significantly (P < 0.01);4.two groups of cases by TCM symptoms Ridit overall efficacy analysis, the treatment group compared with controls (P < 0.05), have both statistical significance;5.two groups after treating patients in TCM symptoms, tongue, compared with medication pulse condition before a statistically significant difference (P < 0.01); Two comparison between qol all had significant statistically significant (P < 0.01); both When the drug by rank and two group of symptoms, all have statistically significant inspection significance (P < 0.01); Before and after the treatment group by rank and drug inspection, the symptoms are statistically significant meaning (P < 0.01); The control group by rank and drug around symptom, all have statistically significant inspection significance (P < 0.01);6.two groups in improving the quality of life of patients with a statistically significant differences on integral significance (P < 0.05). And the two groups of patients treated, the quality of life score improved obviously, compared with before treatment are the significant difference (P < 0.01 or P < 0.05). After treatment, the quality of life in treatment group total score compared with controls, there is significant difference (P < 0.01). ;7 two groups of patients were not significantly or serious adverse reactions, safety and tolerability is good.Conclusion1.fundermental Chinese medicine in the treatment of chronic heart failure patients with chronic heart failure, the heart function to improve the effect of western norms with simple the therapeutic effect of TCM syndrome in improving, equivalent of ho effect-acting period and curative effect on better than control.2.TCM can obviously improve qi qi and Yin deficiency type two symptoms in patients with chronic heart failure. Especially in to improve heart palpitations, chest tightness, shortness of breath, fatigue, dizziness main symptom and tongue has very obvious pulse treatment function.3.fundermental Chinese medicine can obviously increase the quality of life of patients with chronic heart failure, and efficacy is obvious better than control.4.fundermental Chinese medicine therapy and chronic heart failure patients without obvious side effects and adverse reaction, is the treatment of chronic heart failure mid effective drugs, in the prognosis of patients with chronic heart failure may have very good value of clinical applications.5. the fundermental Chinese medicine represents qi method in chronic heart failure in the medium-term intervention has obvious effect, there are important research value. |
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