Ldf And Spect-ct Predicted That Early Traumatic Femoral Head Necrosis

Objective The purpose of the study was to predict the traumatic avascular necrosis of the femoral head by Laser Doppler Flowmetry and SPECT-CTmethods 18 adult Beagle dogs were divided randomly into three equal-sized (n=6) groups. The right hip underwent blood interruption. Group A:cutting off the ligamentum teres, group B:destruction of the marrow cavity of the femoral neck and group C:in addition to cutting off the ligamentum teres and destruction of the marrow cavity, the soft tissue at the base of the femoral neck was stripped. Through a lateral approach, the Laser probe was placed at the subchondral area of the femoral head. Laser Doppler measurements were obtained before the operation. Immediately after the operation, LDF examination was performed and 925～1110 MBq 99mTc-methylene diphosphonate was injected intravenously. At last, LDF and SPECT/CT examination were performed three hours later. Magnetic resonance imaging (MRI) was performed and the dogs were sacrificed for histology examination at the 8th week after the operation.Results Cutting off the ligamentum teres or destruction of the marrow cavity caused a temporary drop in the blood supply of the femoral head, but the femoral head would soon be compensated completely in group A and in group B. In group C, compared with the first measured value, the second significantly reduced by 89%(P<0.001) and never return to the normal range within 3 hours. MRI and histology analysis showed no necrosis in all 12 dogs in group A and group B at the 8th week after the operation. However, all 6 dogs in group C (100%) developed AVNFH.Conclusions LDF and SPECT-CT are helpful to predict avascular necrosis of the femoral head.