Analysis Of Causes Of Chronic Cough Children And Clinical Features

Chronic cough is that cough last longer than four weeks, divided into specific and non-specific cough . cough-specific symptoms for some specific one, in addition to cough accompanied by other symptoms outside.non-specific cough is that cough as the main or sole symptom, Chest radiological examination is normal. chronic cough is non-specific cough. Because of their complex etiology for clinical diagnosis and treatment of a doctor facing a difficult, since 1981 Irwin develop diagnostic procedures for adults with chronic cough since the anatomy, the current causes of chronic cough in adults have some knowledge after 20 years of research.The anatomical structures and imperfect development of the immune system in children, cause of chronic cough has its own characteristics, the 2008 Branch of Chinese Medical Science breathing moment to the American Studies Group of Chest Physicians, 2006 (ACPP) "Clinical follow children with chronic cough Certificate Practice Guide "developed country" diagnosis and treatment of children with chronic cough Guide (trial). " Guide to determine the definition of children with chronic cough, etiology, diagnosis and diagnostic procedures and treatment, and that children of all ages with chronic cough due to different causes, will be to guide clinical diagnosis and treatment of children with chronic cough medical uniform standards. If major cause of chronic cough in our country is the same with the United States, we have not large-scale, multi-center epidemiological survey to confirmed. In order to clarify the cause of our children with chronic cough compared with the distribution and composition, in April 2009, the Chinese constitute a cause of chronic cough in children than in multi-center research project was officially launched, the research sub-project in Shaanxi Province.objective To investigate the clinical features and the major causes of children chronic cough in Xi'an.The clinical data were collected and analyzed.Methods A total of 180 cases of chronic cough hospitalized between 2009-2010 were recruited in Xijing Hospital and the Second Affiliated Hospital of Xi'an Jiaotong University. All children with cough duration≥4 weeks, chest X ray was normal. According to diagnostic process of "diagnosis and treatment of children with chronic cough Guide " ,all children underwent skin prick allergy test, 8 years old children underwent pulmonary function and bronchial provocation (diastolic) trial, under the age of 8 children moisture of lung function tests, according to the need for ENT and skull X ray or CT and Mycoplasma antigen antibody test, fill out the questionnaire.Results Of the 180 cases,106 were male and 74 were female,M/F=1.43:1.The patient's age ranged from 8 months to 13 years, mean 6.2±2.96 years.of chronic cough in children under 1 year old children CVA in 1 case; 1 to 3 years old in 10 cases of postinfectious cough, UACS in 5 cases, CVA in 5 cases, 4 cases of unexplained cough, multiple factors cough in 1 case; 3 to 6 years old children in 17 cases after infection, UACS in 26 cases, CVA in 19 patients, cough of unknown etiology in 11 cases , multiple factors cough in 1 case, other causes of cough in 2 cases (including 1 case of tic sign, and 1 case tongue base cyst); 6 years old children with cough postinfectious cough in 10 cases, UACS in 22 cases, CVA in 31 cases, 6 cases of unexplained cough, multiple factors cough in 7 cases, GERC in 1 cases and psychogenic cough in 1 case.CVA, UACS, postinfectious cough are major cause of chronic cough in Xi'an. To investive the three diseases clinical features,including cough duration, onset time of cough, cough associated symptoms, cough nature, parent smoking, family history of allergy and allergen skin prick test, pulmonary function, the relevance of Mycoplasma test results. Three diseases and cough duration (P<0.05), dry cough (P <0.05), exercise increased (P<0.05), allergen skin prick test (P <0.01), bronchial provocation (diastolic) test significantly ( P <0.01); with cough onset, with symptoms of cough, smoking, family history of allergies such as no significant correlation (P<0.05).Conclusion This paper collected 180 cases of chronic cough in children in Xi'an 116 cases (64.4%), Xi'an surrounding counties and cities in 46 cases (25.6%), which can be representative of the general situation of Xi'an and the surrounding counties; children with chronic cough causes more complex Xi'an and the surrounding parts of the main causes of chronic cough are: CVA, UACS, and postinfectious cough, three children with chronic cough illness accounts for 81.1%; CVA in children with cough duration of the longer, more than half of children with persistent cough 3 months or more, characterized by dry cough cough, activity increased after; infection generally shorter duration of cough,Over 80% of children with cough duration of less than 8 weeks. Skin allergy prick test, older children pulmonary function and bronchial provocation (diastolic) test in the diagnosis of CVA play an important role, the test results will help CVA, UACS and postinfectious cough identification, the body's allergic reactions may be involved in BHR pathophysiology. In accordance with the "Guide to Diagnosis and Treatment of children with chronic cough (Trial)" Diagnostic procedures for diagnosis, 88.3% make clear the cause of chronic cough in children.