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Preparation And Performance Study Of Medical Hydrocolloid Dressings

Posted on:2015-01-10Degree:MasterType:Thesis
Country:ChinaCandidate:F Z ZengFull Text:PDF
GTID:2181330467950047Subject:Materials Processing Engineering
Abstract/Summary:PDF Full Text Request
Medical hydrocolloid dressings is make water colloid particles and rubber blend into a high-tech material injury.The material at the same time with water gel water absorbability and the bonding of the rubber base material, apply on the wound dressings paste rubber base material after the wound, while water colloid particles after absorbing water swelling, to wound with a wet airtight environment, promote wound healing.Medical hydrocolloid dressings are widely used in dermatology, infectious ulcers, bedsore, medical fields such as surgical wounds.Medical hydrocolloid dressings Squibb company by the United States for the first time in1963production use, through many years development, have developed different types and USES of medical hydrocolloid dressings.At present, the medical hydrocolloid dressings improve performance mainly from two aspects:the one, the rubber base material;Second, the water colloid particles.This topic research from two aspects of rubber base material and water colloid particles of the medical hydrocolloid dressings, excellent performance is prepared.With the rosin glyceride, naphthenic oil with SIS,4010, PIB three kinds of continuous phase matrix preparation of hot melt pressure sensitive adhesive as rubber base material of medical hydrocolloid dressings, and the optimal formula through orthogonal experiment.On the basis of further study on rosin glyceride, naphthenic oil4010, dosage of PIB three kinds of continuous phase and matrix influence on medical hydrocolloid dressings, adhesive performance, and to make a preliminary discussion on its mechanism of action. When rosin glyceride content is23.36%, naphthenic oil4010content is9.90%, the PIB content was12.90%, the viscous force can stick to30steel ball at the beginning of a viscous fluid at60min,180°peel strength reached0.9KN/m.By measuring the different medical hydrocolloid dressings products at home and abroad of24h water quantity, as the reference standard combined with CMC, X-CMC, gelatin, such as the absorbent of colloidal particles, ultimately determine the scope of the water content of colloid particles of40-55%.Respectively the CMC with X-the combined effect of CMC, gelatin, pectin, discusses their medical hydrocolloid dressings for24h, water quantity, swelling, the influence of integrity.CMC content is20%, X-CMC content was30%, medical hydrocolloid dressings, water absorbing capacity of up to5014g/m2, complete was87.6%, the swelling property was148.3%.
Keywords/Search Tags:medical hydrocolloid dressings, Water gel, Sodium carboxymethylcellulose, The rubber base material
PDF Full Text Request
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