Study On The Correlation Between Recessive Blood Loss And Blood Stasis Syndrome During Perioperative Period Of Hip Fracture

At present, the surgical treatment of hip fracture has become the consensus of the Department of orthopedics.In the clinical work,when we estimate the perioperative blood loss,we also ignore the hidden blood loss,leading to inadequate estimation of blood loss.Hidden blood loss prolong the recovery time of postoperation,and increase the risk of complications.For hidden blood loss, there is no reliable preventive measures, and the treatment is relatively finite.According to the theory of traditional Chinese medicine, the hidden blood loss can be attributed to the hemorrhagic syndrome.Currently,there is no systematic study on the syndrome and pathogenesis of hidden blood loss in traditional Chinese medicine.According to the characteristics of the syndrome during the perioperative period of fracture and the mechanisms of blood stasis syndrome,the hidden blood loss at perioperative period of hip fracture is related to blood stasis syndrome. Through the study on the relationship between hidden blood loss and blood stasis syndrome in the perioperative period of hip fracture,we want to provide evidence for the study on the syndrome of hidden blood loss,and to provide clinical ideas for the syndrome differentiation and treatment of it.1. ObjectiveThrough the exploring of relationship between hidden blood loss and blood stasis syndrome at perioperative period of hip fracture,to provide evidence for the study of hidden blood loss and clinical ideas for the syndrome differentiation and treatment of it.2.MethodUsing the method of the study of the syndrome, all the patient that meeting the standards of case selection criteria will be included in the statistics.According to the standard scoring method for diagnosis of blood stasis syndrome, the symptom of blood stasis is quantified in the 1st day and 3rd day after operation. At the same time, the volume of hidden blood loss was calculated in the 1st day and 3rd day after operation.According to the scoring of the blood stasis syndrome, the patients are divided into 3 grades of mild blood stasis syndrome, moderate blood stasis syndrome and severe blood stasis syndrome.Using the single factor analysis to observe whether there is significant difference between the volume of hidden blood loss in different groups.According to the statistical results, we can discuss the relationship between blood stasis syndrome and hidden blood loss during perioperative period of hip fracture.3.ResultBy person correlation analysis,1 day after surgery, the hidden blood loss and blood stasis syndrome integral were positively correlated.It’s indicate that 1st day after surgery,with the increasing of the blood stasis syndrome integral, the volume of hidden blood loss is also increase. According to the blood stasis syndrome integral,,the patients is divided into 3 groups: mild blood stasis syndrome, moderate blood stasis syndrome and severe blood stasis.1st days after surgery, with mild blood stasis syndrome,patients’hidden blood loss volume is 395.69±8.74 (ml); with moderate blood stasis syndrome,patients’hidden blood loss volume is 456.61±23.86 (ml);with severe blood stasis syndrome,patients’hidden blood loss volume is 562.97±44.88 (ml). By One-way ANOVA, the volume of hidden blood loss between these 3 groups was statistically significant in the first day after operation.Furtherly using the LSD method,it’s indicate that the 1st day after operation,with moderate blood stasis syndrome,the patients’hidden blood loss volume was significantly higher than that of patients with mild blood stasis syndrome.With severe blood stasis syndrome, the patients’hidden blood loss volume is larger than the previous two.It’s proved that the higher the score of blood stasis syndrome, the greater the hidden blood loss.By person correlation analysis,3 days after surgery, the hidden blood loss and blood stasis syndrome integral were positively correlated.It’s indicate that 1st day after surgery,with the rising of the blood stasis syndrome integral, the volume of hidden blood loss is also increase.3 days after surgery, with mild blood stasis syndrome,patients’hidden blood loss volume is 403.34±42.06(ml); with moderate blood stasis syndrome, patients’hidden blood loss volume is 506.33±31.91(ml);with severe blood stasis syndrome,patients’hidden blood loss volume is 665.14±66.81(ml). By One-way ANOVA, the volume of hidden blood loss between these 3 groups is statistically significant 1 day after operation.Furtherly using the LSD method,with the rising of blood stasis score, the volume of hidden blood loss increase step by step.The average value of blood stasis syndrome score in 40 cases is 31.88±16.08 in 1 day after operation, the average value of blood stasis syndrome score in all cases is 43.80±16.69, and the two groups were statistically significant.40 cases of patients after 1 day of operation,the volume of hidden blood loss is averaged 463.02±72.87 (ml), after 3 days of operation,the volume of hidden blood loss is averaged 533.59±116.58 (ml), the data of the two groups is statistically significant difference.To observe the relationship between blood stasis syndrome score and the volume of hidden blood loss, we found the volume of hidden blood loss and blood stasis score gradually increase over time,they are similar in variations. 4.ConclusionThe results showed that the volume of hidden blood loss in 1 day and 3 days after surgery increase with the rising of the blood stasis syndrome score, which confirmed that the volume of hidden blood loss and blood stasis syndrome during perioperative period in hip fracture have positive correlation with the statistical point of view.This clinical observation show hidden blood loss and blood stasis syndrome are closely related, so we think that blood stasis syndrome is one of the main pathogenesis of hidden blood loss.