Study On Distribution Of TCM Syndromes In Cardiovascular And Cerebrovascular Diseases With Depression

Objective:To study the distribution pattern of TCM syndrome presented on patients with depression in addition to cardiovascular and cerebrovascular diseases, to discuss the clinical significance of sole diagnosis of deficiency of liver yang, and to provide a theoretical foundation for the clinical treatment to depression according to syndrome differentiation.Method:287 cases from cardiovascular division, department of neurology and utpatient during September 2014 and December 2015 in Dongzhimen hospital of Beijing university of Chinese medicine were analyzed from general profile, basic history, previous medical records and complication. Sentimental disorder scale include Hamilton depression scale (HAMD) depression syndrome scale, expert rating scale of TCM syndrome factors of depression and depression liver yang deficiency. All data were imported to a database, the frequency were statistically analyzed by SPSS 17.0 software as well as a chi-square analysis on deficiency of live yang, stagnation of liver qi and deficiency of kidney. The statistically clinical significance between deficiency of live yang and stagnation of liver qi is estimated. A chi-square analysis on TCM syndrome of cardiovascular and cerebrovascular diseases with depression is done, and the distribution pattern of TCM syndrome presented on patients with depression in addition to cardiovascular and cerebrovascular disease is discussed.Results:1 statistical result:Among the 287 cases studied,133 of which is male patient,154 female cases and the average age is 63.98±13.85.Depression associated with cardiovascular disease group of 81 people, pure cardiovascular disease group of 85 people; Depression associated with cerebrovascular disease group of 65 people, the simple cerebrovascular disease group of 63 people. From table 1 know depression and the depression group age distribution has no statistical significance.From table 2 can be depression and the depression group sex is not significant; From table 3 know depression and the depression group compared with manual Labour and mental Labour was no significant statistical difference; By table 4 known degree of depression and the depression group university culture is no statistical difference; Depression and the depression group junior high school or above degree of cultural comparison difference was statistically significant; Degree of depression, the depression group under primary and cultural comparison, the difference was statistically significant.2 Result on liver yang deficiency, liver stagnation and kidney deficiency:liver yang deficiency and liver stagnation show clear clinically statistical significance. Liver stagnation is attributed to emotional upset which could lead to the catharsis failure of liver and thus form the depression of liver qi. That the flowing course of the liver meridian is blocked is the real syndrome. Liver yang deficiency means the deficiency of Liver yangqi, the malfunction in catharsis and blood storage of liver and the pathological change caused by internal deficiency cold. There is no significant difference between liver yang deficiency and kidney deficiency in statistics.3 Result of TCM syndrome analyses on cardiovascular and cerebrovascular disease: TCM syndrome distribution shows that most patient with depression have liver stagnation, followed by heart deficiency, kidney deficiency and spleen deficiency. Cardiovascular patient with depression have a higher chance of showing syndromes like liver depression, stagnation of the circulation of vital energy, phlegm, heart deficiency, spleen deficiency and kidney deficiency than that of patient with cardiovascular disease. Cerebrovascular patient with depression risk more with syndromes of liver depression, stagnation of the circulation of vital energy, heart deficiency, kidney deficiency and yin asthenia than that of patient with cerebrovascular disease.Conclusion:Age and education level have impacts on depression to some extent. There is indeed difference between liver yang deficiency and liver stagnation, and clinical treatments should be differently dealt with. Patients with cardiovascular disease mainly show TCM syndromes of liver stagnation and deficiency of heart and kidney, while spleen deficiency and phlegm appeal more to patients with depression. Patients with cerebrovascular disease mainly show TCM syndromes of liver stagnation, deficiency of heart and kidney would most probably accompany patients with depression.