Research On Professor Zhang Shuxin 's Experience In Treating Chronic Constipation Based On Data Mining

Background:Constipation is one of the anorectal clinic Common diseases, and the Clinical manifestation of Constipation is:the too long cycle of defecation, or dry and hard fecal without long cycle, feeling of incomplete evacuation with no hard stools. Constipation is one of the common clinic symptoms, but it is also a kind of disease in T.C.M. Constipaition which course of disease course was more than six months was belong to Chronic Constipation. Traditional Chinese medicine medical treatment have an advantage in treating Chronic Constipation. Different from the western medicine, traditional Chinese medicine find the basic causes of disease to treat Chronic Constipation by dialectical treatment of TCM, determination of etiologic factors based on differentiation. Doctor zhang Shuxing has focused on teaching and clinical practice of treating Chronic Constipation for years and accumulated a wealth of experience. Also he has achieved a satisfactory clinical efficacy.Objective:Apllying Data Mining technology to do some exploratory research of professor Zhang Shuxin’s clinic medical cases treatment of treating chronic constipation. Diging the ideas of professor Zhang Shuxin’s syndrome differentiation and pharmacy, to provide a new method to inherit professor Zhang Shuxin’s experience of traditional Chinese medicine.Methods Selecting 144 patients which diagnosed to be Chronic Constipation by professor Zhang Shuxin in Dongzhimen hospital anorectal clinic during January 2015 to January 2016. All the data basis of the original information accurately recorded in "basis data processing system", and then in the "basis data processing system" for data preprocessing. Then import in "the basis of traditional Chinese medicine database system ", applied general descriptive analysis、frequency analysis、 correlation analysis with other statistical data analysis, to get data mining results, finally the results are discussed and got the conclusion.Result:1. Those 144 cases in the study have 42 men (29.16%),102 women (70.84%), and the ratio of men and women’s number is 1:2.43. Classified by age:40 (27.78%) patients’age are less than 40,45(31.25%) patients’age are between 40 to 59,59 (40.97%) patients’ age are more than 60; 2. Analysis of etiology and pathogenesis. The main causes of chronic constipation: long illness and weakened body resistance,:Improper diet, the disorder of seven emotions, old and feeble, weak constitution, cold invasion, The top ten pathogenesis are:Yin deficiency, qi and Yin deficiency, sinking of qi due to spleen deficiency,spleen qi deficiency, spleen and stomach qi deficiency, blood deficiency bowel dryness, stagnation of qi activity, qi and blood deficiency, lung and spleen qi deficiency, spleen and kidney deficiency, spleen kidney Yang deficiency. It can be found that Yin deficiency, qi deficiency, blood deficiency, qi stagnation and Yang deficiency are the main pathogenesis. The frequency analysis of the etiology and pathogenesis reflected that the main pathogenesis of clinical constipation patients mainly is weakened body resistance; 3. Dialectical constipation patients mainly are qi deficiency syndrome, Yin deficiency syndrome, qi and Yin deficiency syndrome, blood deficiency syndrome, stagnation of qi activity syndrome, qi and blood deficiency syndrome, Yang deficiency syndrome, gastrointestinal hot and humid, intestines and stomach heat syndrome, congealing cold and qi stagnation syndrome; 4. Selecting the top 15 of the frequency analysis of signs and symptoms results. The common tongue and pulse are red tongue, little moss, reddish tongue, white moss, thin white moss, pulse count and the thin yellow moss. The common symptoms are:dry stool, irregular defecation, anorexia, languid, abdominal distension, dry mouth, poor sleep and difficult defecation. Partly reflects that the clinical constipation patients are usually belong to Yin deficiency, qi deficiency; 5. The analysis showed that the disease’s location of chronic constipation disease mainly are large intestine, spleen, stomach, liver, kidney and lung; 6. The analysis showed that the mainly treatment of chronic constipation are invigorating spleen and replenishing qi, supplementing qi and nourishing yin, nourishing blood and replenishing blood, promoting circulation of qi, reinforcing qi-blood; 7. Professor Zhang Shuxin treats chronic constipation frequently use chinese medicinal materials are raw atractylodes, angelica, citrus aurantium, white peony root, wine desert cistanche, giant knotweed, hemp seed, cassia seed, radix rehmanniae, honey asters, poria cocos, rehmannia glutinosa, cohosh, radish seed, radix astragali, radix scrophulariae, bark of magnolia, fleece-flower root,, pseudostellaria root, radix ophiopogonis, peach kernel, bitter orange, medicated leaven, bunge cherry seed, raw licorice, betel nuts, alisma, snakegourd fruit, rhubarb. Most of the chinese medicinal materials’ effect are tonifying deficiency, promoting the circulation of qi and moistening the intestines. And the the most commonly used chinese medicinal materials are raw atractylodes, angelica, citrus aurantium and white peony root.Conclusion:Main pathogenesis of chronic constipation are qi deficiency, blood deficiency, Yin deficiency and Yang deficiency. The main disease location are large intestine, spleen, stomach, lung, kidney. The treatment of chronic constipation mainly is tonifying deficiency. Professor Zhang puts forward that treating constipation based on tonifying deficiency, treating from lung, and treating from the kidney. Finding the basic pathogeny is the most important thing to cure chronic constipation diseases. Professor Zhang is good at using chinese medicinal materials such as raw atractylodes, angelica, citrus aurantium, white peony root, wine desert cistanche, giant knotweed, hemp seed, cassia seed, radix rehmanniae, honey asters, poria cocos, rehmannia glutinosa, cohosh, radish seed and radix astragali to curing chronic constipation.