Clinical Study On Improving The Phenomenon Of Thirst In Patients With Hemodialysis By Traditional Chinese Medicine

1 ObjectiveIn maintenance hemodialysis patients with thirst symptoms, the most common syndrome of Qi-Yin deficiency with dampness and blood stasis syndrome. This study plays a TCM syndrome differentiation characteristics, from both specimens to establish method. Through randomized clinical study and control, the purpose of this study is to observe and evaluate the Chinese herbal tea to improve maintenance effectiveness and safety of thirst symptoms in hemodialysis patients.2 MethodsThis study selected 60 patients with dampness and blood stasis syndrome of Qi-Yin deficiency in hemodialysis patients with thirst, In the Blood Purification Centre of Wangjing Hospital with China Academy of traditional Chinese medicine. For both specimens, all patients were randomly divided into treatment group and control group.The two groups were treated with conventional Western Medicine. The treatment group was treated with small package of Chinese herbal tea in the thirsty. And the control group by drinking water to relieve thirst.2 groups were observed for four weeks. Through the observation of the before and after the change of xerostomia questionnaire (XQ) to evaluate the improving of the Chinese herbal tea to maintain efficient hemodialysis patients with symptoms of thirst. By observing the relative value of average interdialytic weight gain, to explore the Chinese herbal tea can control in hemodialysis patients in interdialytic weight increase. Through the observation of dialysis adequacy, to evaluate the Chinese herbal tea if it can influnce the dialysis quality of hemodialysis patients. Through the observation of the serum potassium level before, in and after treatment, to evaluate the safety evaluation of the Chinese herbal tea.3 Results3.1 Study completionIn this study,60 patients with maintenance hemodialysis were enrolled, and 5 patients were shed. In the treatment group,3 cases of gastrointestinal discomfort due to the treatment process can not adhere to the initiative to give up. And 1 cases stopped treatment for referral. And 1 cases can not continue treatment due to cancer. Finally,55 cases were included in the effective cases.3.2 Baseline analysisIn the age, gender, duration of dialysis, diabetic patients were distributed, treatment of XQ scores, thirsty severity distribution, the two groups before treatment the average interdialytic weight increased, the relative values of serum potassium treatment and treatment before the dialysis adequacy, there was no significant difference in baseline between the two groups (P> 0.05).3.3 Curative effect analysis3.3.1 XQ scoreAfter treatment, the XQ score of the treatment group was lower than that before treatment. After t test P< 0.05, the difference was statistically significant. After treatment, the XQ score of the control group was compared with that before treatment. By t test, P> 0.05, the difference was not statistically significant. After treatment, the XQ score of the treatment group was lower than that of the control group. After t test, P< 0.05, the difference was statistically significant. After treatment, two groups of patients with thirst severity distribution, by χ2 test facility, P< 0.05, the difference was statistically significant. In the treatment group, severe thirst was reduced from 11 cases to 3 cases,while the number of the patients in the control group had no change compared with before.3.3.2 Average relative value of weight gain in dialysis intervalAfter treatment of two groups of patients in the treatment of first week, the second week, the third week and around, the average interdialytic weight increase relative value difference were not statistically significant, by t test, P> 0.05. Compared with this group before treatment, in the first week, second weeks, third weeks and four weeks after treatment, the average relative value of the average dialysis interval weight increase was not statistically significant, by t test, P> 0.05. However, during the four weeks of treatment, the average weight gain of the treatment group was decreased, while the control group showed no significant change.3.3.3 Dialysis adequacyTwo groups of patients after treatment of Kt/V, URR value of the difference was not statistically significant, by t test, P> 0.05. Compared with the group before treatment, by t test, P> 0.05, the difference was not statistically significant.3.3.4 Blood potassiumThere was no significant difference in serum potassium values between the two groups after treatment, by t test and non parametric test, P> 0.05. There was no significant difference between the groups before treatment and t test and non parametric test, P> 0.05. There were no statistically significant differences in two groups of patients at the end of the first course of treatment, the second course of treatment the number of patients with hyperkalemia comparison, through the examination of χ2 (P> 0.05).4 ConclusionChinese herbal tea can effectively improve the symptoms of thirst in hemodialysis patients. Chinese herbal tea can reduce thirst degree in patients with hemodialysis.Oral administration of Chinese herbal tea average interdialytic weight gain of treatment group decreased relative value. No significant effect of full blood potassium, Chinese herbal tea for hemodialysis patients with dialysis.