Internal Membrane Dystopia Ⅰ Number Side Treatment Lacking In Vital Energy Blood Stasis Endometriosis Clinical Observation

Objective:This study of Chinese medicine through analysis and comparison of endometriotic No. I medicine mifepristone tablets side and two sets of Qi and blood stasis in the treatment of endometriosis-based Comparison of therapeutic effects, including analgesic effect, TCM efficacy, partial Comparison of signs and so on, revealing No.Ⅰmedicine Endometriosis Endometriosis Treated by the unique nature and to explore the treatment of this side Endometriosis mechanism of action.Methods:All patients were from the Jingzhou City Chinese Medicine Hospital from March 2008 to May 2009 gynecological clinics and wards, according to medical inclusion criteria and exclusion criteria,58 patients were collected to observe the patients, using clinical observations, randomized controlled method of will be divided into treatment group (oral endometriosis I Recipe) 30 cases and the control group (oral medicine mifepristone tablets) in 28 cases. Observe the analgesic efficacy of clinical symptoms before and after treatment, anti-endometrial antibody, serum CA125 and serum PRL, E2 level changes.Results:(1) The total clinical efficacy of the two groups to observe the group, the total effective rate was 86.67%, the control group total effective rate was 64.29%), the difference was statistically significant (p<0.05). (2) After treatment, the two groups dysmenorrhea points of comparison, the observation group dysmenorrhea points after treatment 5.09±3.73, treatment group, 5.13±3.68, no significant difference by comparison (p> 0.05) pre-treatment groups in clinical symptoms, serumCA125, reproductive hormone levels, etc. There was no significant difference (p> 0.05). (3) The effect of two groups of traditional Chinese medicine symptoms compared to symptoms of traditional Chinese medicine treatment observation group the total effective rate 90.00%; the control group, the total efficiency of 64.29%, the two groups there are differences between the two groups (p<0.05). Treatment group in improving the anus bulge, anorexia, loose stools, fatigue, etc. Jiaoyou Shenpi, compared with control group significant difference (p<0.05). (4) After treatment, changes in the posterior vaginal fornix tenderness nodules compared to the observation group nodules disappeared in 6 cases, effective in 15 cases, the total effective rate 87.50%; the control group nodules disappeared in 3 cases, effective in 8 cases, total effective rate of 61.11%, two groups between the two groups had significant difference (p<0.05). (5) in the treatment of patients with one-year follow-up after recurrence was observed in relapse rate 10.71%, significantly lower than the control group 34.62%, the difference was statistically significant (p<0.05). (6) before and after treatment CA125, the observation group after treatment CA125 to 13.80±8.45, control group after treatment CA125 to 18.46±8.23, comparison between two groups there was significant difference (p<0.05). (7) peripheral blood before and after treatment EMAb potency compared to the observation group after treatment EMAb positive rate of 23.33% in the control group EMAb positive rate of 21.43%, no statistical significance (p> 0.05). (8) changes in PRL before and after treatment to observe the group after treatment 13.32±3.90, control group was 23.12±6.52, there are statistically significant differences (p<0.05).Conclusion:The treatment of endometriosis-ⅠFang Qi and blood stasis type of endometriosis has a good analgesic effect, and can improve the clinical symptoms and signs of local, lower serum CA125 and serum PRL levels, no significant side effects and adverse reactions. Its mechanism may be adjusted by lowering estrogen receptor (ER, PR) role, reducing ER, PR on estrogen responsiveness and improve the hypothalamus-pituitary-ovarian gonadal axis function, regulating endocrine regulatory mechanisms; and regulate autoimmune function, inhibit endometrial growth, improve local blood circulation and many other links, so as to achieve pain Tiaojing to improve the clinical symptoms and so on.