Analysis The Levels Of C-reactive Protein In Acute Exacerbation Of Chronic Obstructive Pulmonary Disease With Hyperglycemia

Objective:To evaluate the changes of C-reactive protein before and after treatment in acute exacerbation of chronic obstructive pulmonary disease with hyperglycemia to analyze its clinical significance.Methods:To select 32 patients with AECOPD and 30 patients with AECOPD with hyperglycemia, To select other 30 cases outpatients with stable COPD as control group. To detect the serum CRP levels of patients with AECOPD (AECOPD group) and patients with AECOPD with hyperglycemia (the hyperglycemia group) before and after treatment, to detect the serum CRP levels of outpatients with stable COPD (the steady group).Results:The serum concentrations of CRP in the AECOPD group before treatment were (79.20±1.55) mg/L, and in the hyperglycemia group were (120.43±10.21) mg/L, The difference between the two groups was statistically significant (P<0.05). And the two groups were higher than the steady group (15.89±3.24)mg/L, the difference between each other was statistically significant (P< 0.05). The serum concentrations of CRP in the AECOPD group after treatment were (17.02±4.14)mg/L, and in the hyperglycemia group patients were (39.16±6.53) mg/L, the difference between the two groups was statistically significant (P<0.05). The difference between the former and the steady group was a lack of statistically significant (P> 0.05), the difference between the latter and the steady group was statistically significant (P<0.05).CRP in the AECOPD group and the hyperglycemia group was statistically significant between before and after treatment (P<0.05).Conclusion:The higher serum concentrations of CRP is associated with COPD inflammation and inflammatory effects of hyperglycemia correlated overlap.