Different To Stroke Hemiplegia Supersession Acupuncture Rats Spasticity PKA Content Of Impact Study

Objective: To observe different to stroke acupuncture supersession rats spasticity hemiplegia PKA phosphorylation influence of horizontal and protein expression, this paper discusses the different cure acupuncture supersession mechanism for paralysis, alleviate acupuncture therapy increased muscle tension provide experiment basis.Methods: Using improved line rat MCAO for bolt legal system model, using three hours after reperfusion Zea Longa four point scoring criteria for neural behavioral score; After the success of the first made modulus 3 days, continuous treatment began treatment for 14 days, once per day; Using neural electrophysiology h-reflex evaluation model and treatment effect; By Elisa test rats PKA of serum level and western blot phosphorylation method to detect rats in the spinal cord dry and protein expression.Results: 1. With lateral H wave latency period,Yang meridians acupuncture group was significantly longer than model group, and model group, Yin meridians acupuncture group, Yin and Yang, and by acupuncture group Finn group, MCPG group chloride with significant difference (P < 0.01, P < 0.05). With lateral h-reflex fall off curves show, Yang meridians acupuncture group H/M value for 1.078±0.1283 supreme, and model group, Yin meridians acupuncture group, Yin and Yang, and by acupuncture group Finn group, MCPG chloride group compared significantly sexual difference (P < 0.01, P < 0.05). 2.Yang meridians acupuncture group significantly improve the brainstem and serum, rats in the spinal cord of PKA phosphorylation level and protein expression, and model group, Yin meridians acupuncture group, Yin and Yang, and by acupuncture group Finn group, MCPG chloride group compared significantly sexual difference(P < 0.01, P < 0.05).Conclusion: 1.Acupuncture significantly inhibited hyperthyroidism and improve the h-reflex, restrain the falloff curves h-reflex spinal motor neuron excitability; 2 Acupuncture therapy to improve stroke hemiplegia spasticity rats in the brainstem and serum, in the spinal cord of PKA phosphorylation level and protein expression, significant difference between groups comparison ; 3.Acupuncture therapy to alleviate post-stroke hemiplegia spasticity, its action for Yang meridians are the strongest, Yin and Yang, the second weakest Yin meridians.