Evaluation Of Ventricular Longitudinal Shrinkage Function In Patients With Early Liver Cirrhosis Using Two-dimensional Speckle Tracking Imaging

Part 1:Evaluation of Left Ventricular longitudinal shrinkage Function in Patients with early liver cirrhosis Using two-dimensional speckle tracking imagingObjective To assess the left ventricular longitudinal shrinkage function in patients with liver cirrhosis with two-dimensional speckle tracking imaging(2D-STI). Methods Echocardiography and Doppler echocardiography were obtained in 34 patients with hepatic cirrhosis and 35 normal persons of corresponding ages underwent .And high frame rate two-dimensional images were recorded from apical long-axis view,four-chamber view and two-chamber view of left ventricle ,then measuring the left ventricular diameter,left atrium diameter,the peak filling velocity of E wave and A wave,E /A ratio ,EF and FS. The peak systolic strain of left ventricular segment were measured using two-dimensional strain software. Results Compared with healthy subjects,left ventricular diameter,left atrium diameter,EF and FS of hepatic cirrhosis patients were not different(P>0.05) ,but the E /A ratio of hepatic cirrhosis was lower (P<0.05),and the peak systolic strain of most left ventricular segment reduced in hepatic cirrhosis were statistically lower (P<0.05), except base segment of each wall and middle segment of back interventricular septum .Conclusions The heart shape ,systolic and diastole function of hepatic cirrhosis were abnormal. Using the 2D-STI can early and accurately evaluate the systolic function of hepatic cirrhosis.Part 2:Evaluation of Right Ventricular longitudinal shrinkageFunction in Patients with early liver cirrhosis Using two-dimensional speckle tracking imagingObjective To assess the right ventricular longitudinal shrinkage function in patients with liver cirrhosis with Speckle Tracking Echocardiograohy.Methods Echocardiography was obtained in 34 patients with hepatic cirrhosis and 35 normal persons of corresponding ages underwent . And high frame rate two-dimensional images were recorded from four-chamber view of left ventricle, then measuring the right ventricular and atrium diameter. The peak strain,strain rate and velocity of right ventricular free wall each segment in systolic,early diastole and during atrial contraction were measured using two-dimensional strain software.Results Compared with healthy subjects,right atrium diameter of hepatic cirrhosis patients was statistically augmentation (P<0.05). Peak systolic strain , strain rate and peak strain rate in early diastole and during atrial contraction of all segments in right ventricular free wall reduced significantly in cirrhosis patients when compared with the contrast people (P<0.05). Peak systolic velocity and velocity in early diastole and during atrial contraction of the middle and base segments in right ventricular were reduced significantly when compared with the contrast people (P<0.05). Although Peak systolic velocity and velocity in early diastole and during atrial contraction of the apex segments in right ventricular were not different (P>0.05).Conclusions 2D-STI can evaluate the right ventricular function of hepatic cirrhosis patients early and accurately . It can call attention to diagnosis and cure cirrhotic cardiomyopathy then improved the prognosis of hepatic cirrhosis patients.