Subclinical Hypothyroidism And Coronary Heart Disease

Objective:To explore the relation between subclinical hypothyroidism and coronary artery disease Methods:147 patients were classified according to coronary angiography in 93 patients with coronary heart disease group,54 patients without coronary heart disease, the CHD group was divided into single-vessel disease, multi-vessel group. All patients were other than pituitary tumor, malignant, familial hyperlipidemia and severe liver and kidney dysfunction, not taking amiodarone, lithium, metoclopramide, iodine, and other effects of domperidone thyroid function Nearly 3 months of drugs, Detection of free T3, free T4, thyroid-stimulating hormone (TSH), total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL-C), low density lipoprotein cholesterol (LDL-C), containing Apolipoprotein A1 (ApoAl), apolipoprotein B (ApoB), records of coronary lesions, the clinical data recorded, through statistical analysis, draw appropriate conclusions.Results:1, subclinical hypothyroidism with thyroid function in patients with normal population in age, sex, smoking, hypertension prevalence, diabetes prevalence there were no significant differences; 2,The single factor analysis of subclinical hypothyroidism and coronary heart disease correlated (OR= 2.112 OR 95% CI1.102-4.546); 3,Stratified according to whether, after suffering from hyperlipidemia is still of subclinical hypothyroidism a risk factor for coronary heart disease; 4,hypertension stratified by whether subclinical hypothyroidism is still a risk factor for coronary heart disease; 5, Multiple Logistic regression analysis showed that subclinical hypothyroidism and other traditional risk factors for high blood pressure, triglyceride (TG) and coronary heart disease is closely related (P<0.05), and its risk factors, and high-density lipoprotein cholesterol (HDL-C) as a protective factor; 6,Do not count with coronary artery disease by increasing levels of TSH levels increased, but the type of coronary artery disease with thyroid-stimulating hormone levels increased and higher levels.