Study On Quality Of Life Of Patients With Poor Ovarian Reserve And Constitution Type In Traditional Chinese Medicine

Objective:Give prel iminary assessment to life qual ity of women with poor ovarian reserve(POR). Investigate distribution characteristics of institution in traditional chinese medicine with poor ovarian reserve., thereby improve the understanding to poor ovarian reserve, laying the foundation for combating the disease.Method:Select women from gynecology clinic in the first affilicated hospital of GUANGZHOU university of traditional chinese medicine between january 2010 to april 2011. Fasting venous blood in the early morning of 2-3 days of the menstrual period, to measure the sex hormone in serum such as FSH, LH,E2 and so on, to the patients with 10IU/L＜bFSH≤40 IU/L, or (and) bE2≥50pg/mL, or (and) bFSH/bLH>3, use the chinese version of world health oganization quality of life measurement scale abridged table (WHOQOL-BREF) and reseach measurement scale for institution in traditional chinese medicine which designed by professor WangQi in Beijing university of traditional chinese medicine to do the reserch.Results:1. In 54 patients with poor ovarian reserve, patients with abnormal scores of WHOQOL-BREF(slight abnormal group+abnormal group) are in the majority, the number is 83.33%.So we know that the quality of life of patients with poor ovarian reserve is somewhat decreased. Compared with normal women, the two groups have significant difference in comprehensive total scores, subjective sensation, ability to do things,life satisfact ion, frequency of some experience,working pressure, sleeping satisfaction and sex satisfaction and so on (P<0.05) although they do not have significant difference in subjecetive total scores and senses after some experience.2. In 54 patients with poor ovarian reserve,the constitution with qi stagnation are the most, in all 31 cases(occupy 57.41%), followed by constitutuion with blood stasis, in all 27 cases(occupy 50.00%), and many arehave multiple constitution, especially the constitution with blood stasis and qi stagnation at the same time counts most, in all 26 cases(occupy 48.15%), andin all the patients with poor ovarian reserve who have only one kind of constitution are 17 cases(occupy 31.48%). constitutuion with qi stagnation in normal control group is also the most, in all 21 cases (occupy 38.89%), followed by constitution with qi defficiency, in all 16 cases(occupy 29.63%). Use chi-square test to compare constitution in traditional chinese medicine between patients with poor ovarian reserve and normal control group, the result showed P<0.05, suggested that the constitution type of patients with poor ovarian reserve and normal control group has signifacant difference.3. Endocrine results of 54 patients with poor ovarian reserve mainly showed 10IU/L＜bFSH≤40 IU/L, in all 28 cases (occupy 51.85%),12 cases in it with solus 10IU/L＜bFSH≤40 IU/L (occupy 22.22%),followed bE2≥50pg/mL, in all 25 cases (occupy 46.30%),14 cases in it with solus bE2≥50pg/mL (occupy 25.93%),18 patients possess 2-3 items of endocrine performance conditions (occupy 33.33%).4. In 54 patients with poor ovarian reserve, delayed menstrual cycle occupy 33.33%, apogeny occupy 25.93%, hypomenorrhea occupy 16.67%, three kinds of disease occupy 75.93% in all.Conclusion:1. Quality of life for the poor ovarian reserve group is decreased, especially appears in subjective sensation, life satisfaction, frequency of some experience, working pressure, sleeping satisfaction and sex satisfaction and so forth.2.Constitution with qi stagnation in traditional chinese medicine are the most for patients with poor ovarian reserve, followed by constitution with blood stasis, and many are have multiple constitution, especially the constitution with blood stasis and qi stagnation at the same time counts most, constitutuion with qi stagnation in normal control group is also the most, followed by constitution with qi defficiency.3. The most commonly endocrine characteristic of patients with poor ovarian reserve is basic FSH goes up.4. Patients with poor ovarian reserve can be diagnosed with traditional chinese medicine as delayed menstrual cycle,hypomenorrhea, apogeny and the diseases like its kinds.