| Traditional Chinese medicine is the treasure of the Chinese nation, as early as thousands years ago, Chinese medicine fermentation has become one of the method of Traditional Chinese medicine firing. In this paper, use the liquid fermentation Traditional Chinese medicine, in order to increase the curative effect, improve the content of effective ingredients, according to these considerations, we take some researches as follows:1.Using step-through test, compared to the influence of invigorating blood circulation and eliminating stasis medicines, relaxes the mind and tonifying spleen medicines, heat-clearing and eliminating phlegm medicines, tonifying the kidneys and liver medicines to memory in mice. The results showed that before mice infused stomach 30 days, each training not statistically significant differences in preclinical.And other traditional Chinese medicine group could extend latent times.2. After four kinds of edible fungi fermentation compared the variation of effective component content in screened Chinese medicine with different time, confirmed the relatively optimal fermentation strains and optimal fermentation time.3.Use single factor experiment and the orthogonal experiment, total saponins and the flavonoids content as the index, optimized the ganoderma lucidum fermentation notoginseng, ganoderma lucidum fermentation astragalus, edible fungi fermentation puerarin cuiture mediums and fermentation conditions.4.By step-down test and step-through test, screened improve memory Chinese medicine compound, and carries on the acute toxicological testing, get formula and confirmed it belongs to non-toxic grade material.5. Finally by several physiochemical index determination, we learned that the the formula can significantly inhibit acetophenetidin vigor (P<0.05), improving Super Oxide Dlsmutase vigor (P<0.01), reduce the content of malondialdehyde, thus through improving central cholinergic nerve system transfer, to produce antioxidant effect to improve memory function.
|
PDF Full Text Request