Data Mining Research On Ancient Prescription In Treating Amenorrhea

Amenorrhea is a common gynecological diseases. With the social pressure, changes in social status of women, the prevalence of female style diet, women increasingly high incidence of amenorrhea, which seriously affects women's reproductive health. Attention to women's reproductive health in traditional Chinese medicine, in the development of thousands of years, traditional Chinese medicine for treatment of gynecological diseases and accumulated rich experience.For the treatment of amenorrhea, therapy of traditional Chinese medicine and hormonal therapy of modern medicine are completely different. Moreover, the TCM medical treatment of amenorrhea has a long history and rich experience. In the "the yellow emperor's canon of internal medicine " recorded the first prescription of treating amenorrhea. Thousands of years, ancient physicians summarizes clinical experience and accumulated many good effects of prescription of treating amenorrhea. From among so many prescriptions mining law of TCM treatment of amenorrhea, summarize the treatment of the ancient physicians, for improving and regulating TCM clinical treatment of amenia today have a good meaning.1.Research purposePurpose of this study is from the excavation of ancient prescription of treating amenorrhea law of TCM treatment of amenorrhea, summarize the treatment of the ancient physicians.2.Research methodsIn this study, the treatment of the Han Dynasty to the Republic of the prescription amenorrhea as research subjects to establish a database, from the scope of drug treatment, indication areas such as analysis. Using statistical software SPSS13.0, data mining tools in the enterprise mining module SAS8.0, respectively frequency analysis, factor analysis, correspondence analysis, association rules, association plans and other operations.3. Study results(1). Treatment of amenorrhea prescription mainly from the Ming and Qing dynasties, the Ming and Qing Chinese Medicine Obstetrics and Gynecology shows a more mature, and many works have spread wider impact. About 1/4 recipe from the Obstetrics and Gynecology monograph.(2). By frequency analysis, we found among the formulae of curing amenorrhea Angelica, chuanxiong, Peony, rehmannia four-Wu-Tang and Cyperus using frequency of regulating menstruation is top. Angelica is the most used drug,20-25% higher than the second effect.(3).Through the associated rules of operation, we have out of curing amenorrhea of medicine, pharmaceutical group. Further analysis of curing amenorrhea associated rules are mainly of siwu decoction combined with Cyperus, Dan, respectively, or a crude in a four-Wu-Tang are replaced by a radix rehmanniae Preparata, or a four-Wu-Tang are glucosides of radix paeoniae Rubra in instead.(4) Through drug link analysis, we find the core treatment drugs group as amenorrhea, szechuan lovage rhizome and Angelica sinensis glucosides, aroma, rehmannia, safflower, Peach kernel, liquorice, nourishing blood and promoting blood circulation, Qi and regulating menstruation in treatment of amenorrhea is the core policy. Angelica is the preferred drug for treatment of amenorrhea.(5). By results of factor analysis, comprehensive analysis, we found that treatment of amenorrhea common treatment strategies have the nourishing blood and activating blood circulation and clearing heat and removing dampness Qi and invigorating the spleen and replenishing qi to invigorate the spleen and tonifying the kidney.(6). Through comprehensive analysis of the results, we found the ancient treatment of amenorrhea, mainly focused on blood, mainly blood deficiency and blood stasis treated two pathological state, and that dysmenorrhea of blood and promoting blood circulation traditional Chinese medicine treatment of dysmenorrhea respectively from the famous two works, one of the "Yellow Emperor's internal classic", was the second of "treatise on exogenous febrile disease and miscellaneous disease".Of course, also has many disadvantages in this study, included the prescription may be incomplete, or where there are omissions, these need to be working further to improve in the future. Do so in the future work of our medical cases of treatment of amenia, comprehensive research to further modify and enrich research conclusions.