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A Clinical Study Of Qiangguhuoxue Decoction Combined With PKP In The Treatment Of OsteoPorotic Thoracolumbar Vertebral ComPression Fractures

Posted on:2012-01-13Degree:MasterType:Thesis
Country:ChinaCandidate:D J WangFull Text:PDF
GTID:2154330335459684Subject:Orthopedics scientific
Abstract/Summary:PDF Full Text Request
Research Objective:The main PurPose of this study is to analyze the clinical efficacy of self-PrescriPtion Qiangguhuoxue Decoction combined with PKP in the treatment of osteoPorotic thoracolumbar vertebral compression fractures. Thus Preliminary evaluate the effectiveness and the security of Qiangguhuoxue Decoction. Discover a better treatment for clinical. The research is to Play in medicine in the treatment of osteoPorotic compression fractures of the unique advantages. Observed the clinical efficacy of chinese medicine treatment of osteoPorotic compression fracture.Research Methods:Arandomized controlled clinical trial design,60 Patients met the selection criteria of elderly Patients with osteoPorotic thoracolumbar vertebral compression fractures were randomly established for the treatment grouP and control grouP. The treatment grouP received PKP and Qiangguhuoxue Decoction.The control grouP received PKP and XLGB caPsules. According to the actual examination of Patients, accurate records of Patient's condition. For efficacy evaluation after three months, the various indicators before and after Research Results:1. Between treatment grouP and control grouP before treatment were not significantly different factors(eg:sex, age, vertebrae and other injuries Vertebrals) (P>0.05). VAS score,the changes of X-ray,bone mineral density,the laboratory indicators and comPared syndromes have no significant difference(P>0.05).2. ComPared with after the first week of treatment and before treatment, VAS scoreand the changes of X-ray have statistically significant difference(P<0.05), bone mineral density. the laboratory indicators comPared syndromes have no significant difference(P>0.05). Differences between the grouPs was not significant(P>0.05).3. Three months after treatment,each grouP of indicators than before treatment were significantly different(P<0.05);comPared with after the first week of treatment, VAS score and the changes of X-ray have no statistically significant difference(P>0.05), bone mineral density and the laboratory indicators have significant difference(P<0.05). TCM symPtoms and signs before and after treatment than treatment are statistically significant differences in a week (P<0.05).GrouPs showed no significant difference(P>0.05).4. During the treatment two grouPs of Patients were no obvious side effects, adverse reactions and allergies. Conclusion:Self-PrescriPtion Qiangguhuoxue Decoction combined with PKP is effective in treating osteoPorotic thoracolumbar vertebral comPression fractures, imProve clinical symPtoms and signs, can greatly imProve the quality of life of Patients OVCF. At the same time the Qiangguhuoxue Decoction was security,effective and cheaP.It was worth to Promoting in clinical.
Keywords/Search Tags:Qiangguhuoxue Decoction, Percutaneous kyPhoPlasty, OsteoPorosis, ComPression fracture, Clinical Observation
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