| Background Acquired Immune Deficiency Syndrome Also known as acquired immune deficiency syndrome, by the human immunodeficiency virus (Human Immunodeficiency Virus, HIV) infection. Since 1981, the United States announced the first case of AIDS cases in the world, the spread of AIDS has been in a trend of rapid growth. Showing the current epidemic of the overall low prevalence situation, but some areas of high prevalence trend has emerged. Pulmonary infection as one of the most common infection, with diversity, mixing and refractory characteristics, for clinical diagnosis and treatment very difficult.Traditional Chinese Medicine for AIDS research in the field has taken shape, the etiology and pathogenesis of AIDS is also a certain awareness, more attention in the treatment of the relationship between global and local, through the combination of righting and dispelling evil, and distinguish the dialectical unity of disease and methods of To improve symptoms, improve immunity, prolong survival and improve quality of life purposes. TCM etiology and pathogenesis of lung disease has its theoretical system, its control has extensive experience and achieved good results. AIDS clinical manifestations of pulmonary infection actual situation mixed, mixed cold and heat, emphasis on traditional Chinese medicine samples in both therapies, supplementation and attack, lung infection and AIDS itself has a good effect. According to traditional Chinese medicine for AIDS and pulmonary infection in the understanding of pathogenesis, combined with clinical characteristics of people with AIDS, according to TCM syndrome differentiation method, prospective, multicenter, randomized control study to explore the pulmonary infection in AIDS treatment for Integrative Medicine And observe the effectPurpose A clear diagnosis of pulmonary infection in AIDS, based on the subjects of clinical trials of 180 cases, while in determining the safety evaluation of Chinese medicine treatment of AIDS clinical pulmonary infection, is involved in Chinese medicine to provide experimental pulmonary infection in AIDS Basis, thus the formation of the appropriate treatment.Subjects and methods This study randomized, multicenter, parallel controlled trial method. The study also conducted in 5 centers, in the 2009.06-2010.10 Yung Shing by phlegm, phlegm lung resistance, lung and kidney syndrome type 3 two losses were combined into the group of 180 patients with pulmonary infection of AIDS patients,120 patients in trial group and control 60 patients, randomly divided into two groups by the central or the control group, experimental group based on Western medicine therapy plus TCM treatment, TCM given corresponding to different syndromes of traditional Chinese medicine, Western medicine control group to the basic treatment of pulmonary infection for 4 weeks. Observations include:clinical indicators, AIDS-related indicators, quality of life scores of patients, efficacy evaluation of TCM, safety indicators, such as the clinical therapeutic efficacy.Results Treatment group and control group compared symptom scores, lung and kidney in the two losses card 7 days 14 days 28 days there was significant difference in the treatment group significantly better than the control group; phlegm dampness and phlegm cardeach observation point the lung resistance were not significantly different.Since the first 7 days of the syndrome to reduce the average rate of more than 30% points, the syndrome before and after treatment P<0.01, significant difference, suggesting that treatment is effective; treatment of both lung and kidney 28 days license loss 79.1%, suggesting thata significant effect, phlegm dampness reduction rate of 64.6% points card, phlegm blocking the lung 65.8%, three points less than the control group rate, suggesting that traditional Chinese medicine effective than the control group.Two main sets of symptoms and disappearance of Analysis:Only the first 14 days of entry in body temperature was significantly different (P<0.05), the treatment group than the control group.Cough, expectoration, shortness of breath, palpitations, body weight difficulties, loss of appetite, quantity of sputum were not significantly different.Quality of life, the treatment group and control group before and after treatment were performed paired samplest test, the results of the treatment group in the total score, physical domain, independence domain scores significantly increased, P values were less than 0.01, significant difference;the control group in the total score before and after treatment were not statistically different in various fields.Conclusion 1.Chinese Medicine Bufei Tang with Qiwei Du Qi Wan for HIV infection in the lung and kidney deficiency of both lungs cards, to better improve the symptoms of lung infection, increase efficacy, shorten the treatment period, efficacy was significantly better than single Western medicine group.2. Decoction for clearing gold in the treatment of AIDS infection in the lungs phlegm dampness and to permit combined Erchen Xiaoqinglongtang phlegm blocking the lung treated with western medicine alone group was no significant difference in efficacy.3. Traditional Chinese Medicine to treat AIDS patients with pulmonary infection may improve the quality of life, especially in the areas of physical capacity and independence. Phlegm dampness; phlegm lung resistance; lung and kidney two losses...
|
PDF Full Text Request