| Objective:To evaluate the effects of early nutrition application on nutritional metabolism and its clinical significance in oral and maxillofacial malignant tumor patients after operation.Methods:40 oral and maxillofacial malignant tumor patients in this experiment were randomly divided into two groups:early nutrition support group (n=20), comparison (normal diet) group (n=20). In the early nutrition support group, the energy requirement is calculated by fimula Harris-Nenedict, then adjusted by situation accordingly, we choose the suitable formulation for patient and feed via suitable route. In the comparison group, the patients are feeded with normal diet. The nutrition supports started within 24 postoperative hours to the 7th postoperative day. The weight, plasma prealbumin, albumin, and total lymphocyte count (TLC) were collected before operation and on the 7th postoperative day. The therapeutic effects of postoperational support were studied.Results: 1 In nutrition support group, the postoperative, plasma ALB, plasma PAB and TLC is significant lower than pre-operation (p<0.05), while postoperative weight and plasma TRF is lower than pre-operation with no significant difference(p>0.05). In comparison group, the postoperative weight, plasma ALB and plasma TRF is significant lower than pre-operation (p<0.05), while postoperative plasma PAB, TLC is significant difference than pre-operation (p<0.01)2 Post-operative weight of both group is lower than pre-opertation, but there is no difference between two groups.(p>0.05)3 petient's wound healing with class I in nutriton support group is higher than camparison with significant difference.(P<0.05)Conclusion:Early nutrition application in oral & maxillofacial malignant tumor patients after operation can improve the nutritional status and recovery as well as the wound healing.
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