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A Comparative Study On "WHO Model List Of Essential Drugs Anti-hypertensive" And "China's Anti-hypertension To Essential Medicines Directory"

Posted on:2010-04-10Degree:MasterType:Thesis
Country:ChinaCandidate:K ZhangFull Text:PDF
GTID:2154330332457937Subject:Pharmaceutical Engineering
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Objective:Through the "WHO Model List of Essential Drugs anti-hypertensive" and "China's anti-hypertension Essential Medicines List" (2009 version) a comparative study for the development of new essential drugs in our catalog to provide inspiration.Methods:Using literature method, retrieved MDLINE, CBMdisc, CNKI and VIP, and trace all the references included in the study, a comprehensive collection of world-wide on the "WHO Model List of Essential Drugs anti-hypertensive" and "China's anti-hypertension Essential Drug List" (2009 version) contained in the received antihypertensive drug treatment of hypertension efficient, price comparison and frequency of use in the hospital; by analyzing the "WHO Model List of Essential Drugs anti-hypertensive" and "China's basic anti-hypertensive drugs" (2009 version)the relevant information, derived similarities and differences between two directories; Through "Our anti-hypertension Essential Medicines List" (2004 version) and "China's anti-hypertension Essential Medicines List" (2009 version) comparing the differences between the two obtained.Results:By the definition of essential medicines and the selection principles and included 322 cases of taking antihypertensive drugs in different situations and some of the hospitals the use of antihypertensive drugs analysis "of China's anti- hypertension Essential Medicines" (2009 version) and " China's anti-hypertension Essential Medicines List "(2004 edition);" WHO Model List of Essential Drugs anti-hypertensive "and" China's anti-hypertension Essential Medicines "(2009 version) collected more antihypertensive drugs contained in the outcome; Results Display:â‘ "China's Model List of Essential Medicines of anti-hypertensive" (2004 version) and "China's anti-hypertension Essential Medicines" (2009 edition) differences are:the amount of drugs significantly reduced:from the original 27 kinds of streamlining of 7 species, At the same time by adding two kinds of compound preparation; to delete the price more expensive drugs, patients reflects the affordability of essential medicines; to delete the obvious effects of treatment, adverse reactions more drugs; but the exact effect of drugs, such as they should be reservations.â‘¡"WHO Model List of Essential Drugs anti-hypertensive" and "China's anti-hypertension Essential Medicines" (2009 version) have in common are:the composition and into the conditions of the same directory, directory, identity conditions of use basically the same, the description of the same dosage form drug dosage form arrangements of the rules are consistent; differences are:different types of drugs include:"WHO Model List of Essential Drugs anti-hypertension," a total of seven categories, including pharmaceuticals, the catalog number of seven kinds of species, the number of standard dose+10; " China's anti-hypertension Essential Medicines List "(2009 version) a total of eight categories, including pharmaceuticals, the catalog number of nine kinds of species, the number of 10 kinds of dosage forms+specification, containing two kinds of compound preparation," WHO Model List of Essential Drugs anti-hypertension "in Select the kind of drugs at reasonable prices of drugs; "China's anti-hypertension Essential Medicines List" (2009 edition) has increased the control necessary for reasonable prices convenient to use the compound preparations containing relevant.Conclusion:From the national essential drug list to see, too many varieties of completely unnecessary, but the coverage is too large variety of easy to increase the public's financial burden to the promotion and use of essential drugs bring difficulties, so for the treatment of acute high blood pressure drugs:nitroprusside sodium, magnesium sulfate and phentolamine; in effect acts as a diuretic antihypertensive drugs:hydrochlorothiazide and indapamide; "WHO Model List of Essential Drugs anti-hypertension" Select a price more reasonable nitroprusside and hydrochlorothiazide; pregnancy chronic long-term treatment of choice for high blood pressure drugs:methyl-dopa, curative effect, but also became the "WHO Model List of Essential Drugs anti-hypertension," contains the basis of income; "China's anti-hypertension Essential Medicines List" (2009 version) reproduces antihypertensive effect strong role in a wide range of low cost compound of reserpine and compound reserpine tablets Triamterene, which is already in China after the development of new anti-hypertension Essential Medicines List, to "WHO Essential Drugs Anti-hypertensive model Directory "is intended to draw on and increased.
Keywords/Search Tags:Essential drugs, anti-hypertensive drugs, selection principles, compound preparation
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