| Objective:To study the effects on other organ function with children respiratory tract infection by clinical observation. To explore the relation in organ function damage to different types of childhood respiratory tract infection and find the response to the emerging pandemic virus and guide the clinical application of drugs for protection organ function, preventing and curing disease as soon as possible.Methods:Fifty-two children who diagnosed with respiratory tract infection in pediatrics of The First People's Hospital of Dalian Jinzhou District from October 2009 to 2010 in January were collected for the study. Among of all,15 patients with upper respiratory tract infection,20 patients with pneumonias (including severe pneumonias),17 patients with influenza H1N1 infection. The venous blood of all patients were collected in the morning on the second day for blood cell analysis, assay biochemical liver function and myocardial enzyme. Anteroposterior chest X-ray and electro-cardiogram were examined selectively. We investigate against clinical data and auxiliary examination, record all the test results for each patient and the date of admission, age, gender and other general and clinical symptoms, signs, treatment, prognosis and prognostic information to comprehensive analysis. The data were analyzed in statistic software of SPSS 10, and the value of p<0.05 was regarded as statistical significance.Results:1. In the upper respiratory tract infection group, the pneumonia group and the influenza H1N1 infection group, the value of CK-MB is 19.15±5.66 U/L,25.52±13.43 U/L,20.72±8.98 U/L. Pairwise comparisons, the results show that P<0.01, there are statistical significance.2. In the upper respiratory tract infection group, the pneumonia group, the influenza H1N1 infection group, the value of ALT is 30.15±18.76 U/L, 43.52±13.42 U/L,48.28±15.88 U/L. Pairwise comparisons, the results show that P<0.01, there are statistical significance.3. In the three groups, there are 27 male children, the incidence rate is 51.92%, and 25 female children, the incidence rate is 48.08%. The results show that the incidence of the disease is analogic in different gender, the difference has no statistical significance.4. The age distribution in the three group is from 6 month to 13 years old, and the average value is 6.35 years.5. There are 11 patients with ex-respiratory system complications,3 patients with myocardial damage, and 8 patients with neutropenia synd-rome.6.Treatment:According to clinical symptoms and laboratory examin-ation results, supply three groups regular treatment:patients with virus infection were given antiviral treatment, patients with WBC steping-up were add to antibiotics, patients with pneumonia were given anti-infection symptomatic treatment. The effects are significant and eusemia. All patients were cured when leave hospital, and the course of treatment is 3-12 day.Conclusion:1.Childhood respiratory tract infection may involve other organ systems easily, the more severe infection, the more obvious involvement. The upper respiratory tract infection involved less, while the pneumonia involved obviously. The change of myocardial enzyme is the most ob-viously.2. There are no sex differences in the three groups patients.3. The age of onset distribute regularly:follow the increase of age the incidence rate of pneumonia is decline, and most patients with common upper respiratory tract infection.4.Pneumonia cause a high incidence of injury on other organ systems, but it has a good prognosis, without fatality case and sequelae.5.The influenza H1N1 onset emergency and progression fasting, it can cause severe complication. But if discovery early and cure correcetly, the effect is excellent. We should pay more attention for it, but do not panic over.6.Application of anti-infection treatment of respiratory tract infection have a good effect. For patients with influenza H1N1, the effect of antiviral drugs is significant. It can improve the efficacy and shorten course of disease, if supplemented by regulation of the immune and other symoto-matic treatment while treatment. |
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