Analysis Of 168 Cases On Surgical And Clinical Treatment Of Thyroid Carcinoma

Objective:thyroid carcinoma, the most common malignant neoplasm of thyroid gland, accounts for about one percent of the malignant tumors of the whole body and about four percent of thyroid diseases. Most of the patients are female and the incidence of this disease is 1.49/0.1 million which will increase year by year. Most of the thyroid carcinoma differentiates well and has low level of becoming malignant.The main treatment measure is surgical treatment which can produce a better effect. Except for the medullary carcinoma, most of the thyroid carcinoma results from follicular epithelial cells. According to pathological types of tumor, thyroid carcinoma can be classified into papillary carcinoma,follicular, medullary carcinoma, undifferentiated carcinoma and so on. The biological feature,clinical manifestation diagnosis and prognosis for thyroid carcinomas of different pathological types are different. By summarizing cases of surgical operation on patients of The Second Affiliated Hospital of Dalian Medical University, composition of the patients of thyroid carcinoma, methods and effects of surgical treatment will be analyzed.Methods:retrospective analysis of the clinical data of 168 thyroid carcinoma operated patients aging from 21 to 55, who hospitalized in The Second Affiliated Hospital of Dalian Medical University from the year 2007 to 2009.Results:the result shows that among the 168 patients, there are 56 male patients and 112 female patients with an incidence rate of 1:2 between males and females. There exists an obvious difference (It has statistical significance when P value<0.05). The average morbidity age is 45 years old and the patients are generally aging from 21 to 50.Among the classifications of tumor tissues, the main type is differentiated thyroid carcinoma accounting for about 69.05% among which papillary carcinoma accounts for 51.79%. The main surgical methods are change of side lobus, glandulae thyroideae, excision of thyroid isthmus and excision of the whole side lobus glandulae thyroideae. In treatment of cervical lymph node, whether lymph node dissection should be made depends on preoperative aspiration biopsy, conditions in operation and pathological examination of fast frozen section. Generally, preventive neck dissection is not to be made.Conclusion:the main thyroid carcinoma of this group is differentiated thyroid carcinoma; surgical methods should be individualized according to nature of pathological changes, TNM and personal situation of patients; only by putting professional trainings, careful operations, and normalized surgical process into practice can incidences of complications be reduced effectively; normalized and systematic hormone inhibition treatment and 1311 treatment when necessary can reduce post operative recurrence rate.